28938-17-2

Basic information

• Product Name: 4,5-DibroMo-2-Methyl-2H-1,2,3-triazole
• Synonyms: 4,5-DibroMo-2-Methyl-2H-1,2,3-triazole;4,5-dibromo-2-methyl-1,2,3-triazole;4,5-dibromo-2-methyltriazole;4,5-dibromo-2-methyl-triazole;2-Methyl-4,5-dibromo-2H-1,2,3-triazole
• CAS NO: 28938-17-2
• Molecular Formula: C₃H₃Br₂N₃
• Molecular Weight: 240.88402
• Mol File: 28938-17-2.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4,5-DibroMo-2-Methyl-2H-1,2,3-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-DibroMo-2-Methyl-2H-1,2,3-triazole(28938-17-2)
• EPA Substance Registry System: 4,5-DibroMo-2-Methyl-2H-1,2,3-triazole(28938-17-2)

Safety Data

• Hazardous Substances Data: 28938-17-2(Hazardous Substances Data)

Usage

General Description

4,5-Dibromo-2-Methyl-2H-1,2,3-triazole is a chemical compound with the molecular formula C4H4Br2N2. It is a type of triazole, a five-membered heterocyclic ring containing three nitrogen atoms and two carbon atoms. 4,5-DibroMo-2-Methyl-2H-1,2,3-triazole is commonly used as a building block in organic synthesis and as a reagent in chemical reactions. Its chemical structure makes it useful for the formation of various pharmaceuticals, agrochemicals, and materials. Additionally, 4,5-Dibromo-2-Methyl-2H-1,2,3-triazole has potential use as a pharmacological compound, with some studies showing its ability to inhibit certain enzymes and target various biological pathways. However, its specific uses and applications are still being explored and researched.

Upstream product

• 18922-69-5 1-methyl-1,2,5-triazole 
• 22300-52-3 4,5-dibromo-2H-1,2,3-triazole 
• 74-88-4 methyl iodide 
• 15294-81-2 4,5-Dibromo-1H-1,2,3-triazole 
• 25537-64-8 1-methyl-4,5-dibromo-1H-1,2,3-triazole 

Downstream Products

• 16681-67-7 4-bromo-2-methyl-2H-1,2,3-triazole 
• 942060-54-0 4-bromo-2,5-dimethyltriazole 
• 885877-41-8 4-bromo-1,5-dimethyl-1H-1,2,3-triazole 

Relevant articles and documents

Amide compounds and uses thereof

Provided herein are novel amide compounds of formula (I), pharmaceutical compositions comprising same, methods for preparing same, and uses thereof, wherein the definition of each symbol is as described in the description.

AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF CONDITIONS RELATED TO THE MODULATION OF IL-12, IL-23 AND/OR IFN-ALPHA

Compounds having the following formula I: or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-2

Preparation method of 1-subtituted-1H-1,2,3-triazole-4-carboxylic acid

The invention provides a preparation method of 1-subtituted-1H-1,2,3-triazole-4-carboxylic acid. The preparation method includes the following steps: 1-substituted-4,5-dibromo-1H-1,2,3-triazole is added to an isopropylmagnesium chloride, such that 1-substituted-4-bromo-1H-1,2,3-triazole is obtained through a reaction; an isopropylmagnesium chloride-lithium chloride complex is added directly, such that a mixture of 1-substituted-1H-1,2,3-triazole-4-carboxylic acid and 1-substituted-4-bromo-1H-1,2,3-triazole-5-carboxylic acid is obtained; a base and iodomethane are added to the mixture, such that methyl 1-substituted-4-bromo-1H-1,2,3-triazole-5-carboxylare is obtained through a reaction; the aqueous layer is adjusted with hydrochloric acid until a pH value is 1-5; extraction is carried out with an organic solvent, and drying and concentration crystallization are carried out, such that 1-substituted-1H-1,2,3-triazole-4-carboxylic acid is obtained. The method is suitable for industrial production, and has a great application value.