28940-47-8

Basic information

• Product Name: 2-(2-{4-nitrophenyl}vinyl)-1H-benzimidazole
• Synonyms: 2-(2-{4-nitrophenyl}vinyl)-1H-benzimidazole
• CAS NO: 28940-47-8
• Molecular Formula: C₁₅H₁₁N₃O₂
• Molecular Weight: 265.26674
• Mol File: 28940-47-8.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(2-{4-nitrophenyl}vinyl)-1H-benzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-{4-nitrophenyl}vinyl)-1H-benzimidazole(28940-47-8)
• EPA Substance Registry System: 2-(2-{4-nitrophenyl}vinyl)-1H-benzimidazole(28940-47-8)

Safety Data

• Hazardous Substances Data: 28940-47-8(Hazardous Substances Data)

Upstream product

• 615-15-6 2-Methyl-1H-benzimidazole 
• 555-16-8 4-nitrobenzaldehdye 
• 882-06-4 4-nitro-trans-cinnamic acid 
• 615-28-1 o-phenylenediamine dihydrochloride 
• 95-54-5 1,2-diamino-benzene 
• 128951-03-1 (E)-1,1-bis(methylthio)-5-(4-nitrophenyl)-penta-1,4-dien-3-one 
• 1476043-81-8 (E)-N-(2-aminophenyl)-3-(4-nitrophenyl)acrylamide 
• 1238855-02-1 C₉H₈NO₆S^(1-)*Na⁽¹⁺⁾ 
• 4857-04-9 2-chloromethyl-1H-benzimidazole 
• 74710-09-1 o-phenylenediamine sulphate 
• 60912-44-9 ((1H-benzo[d]imidazol-2-yl)methyl)triphenylphosphonium chloride 

Downstream Products

• 28940-48-9 (E)-2-(4'-aminostyryl)-1H-benzimidazole 
• 1620567-37-4 (E)-4-chloro-N-((2-(4-nitrostyryl)-1H-benzo[d]imidazol-1-yl)methyl)aniline 
• 1620567-13-6 (R)-2-(4'-chlorophenyl)-3-(4'-nitrophenyl)-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2-c]pyrimidin-4-ol 
• 1620567-55-6 4-chloro-N-((2-((2S,3S)-3-(4-nitrophenyl)oxiran-2-yl)-1H-benzo[d]imidazol-1-yl)methyl)aniline 

Relevant articles and documents

α-Aroylidineketene dithioacetal chemistry: CuI catalyzed synthesis of 2-styryl benzimidazoles enroute to regioselective hydrothiolation

Abstract Reactivity of α-aroylidineketene dithioacetals 2 was investigated to synthesize novel 2-styrylbenzimidazole derivatives 4 and their hydrothiolated product 2-(2-(methylthio)-2-arylethyl)-1H-benzo[d]imidazoles 5 has been reported. Compounds 4 and 5

From a Multipotent Stilbene to Soluble Epoxide Hydrolase Inhibitors with Antiproliferative Properties

Inspired by nature: Natural product isopropylstilbene was identified as an inhibitor of soluble epoxide hydrolase exhibiting antiproliferative properties. Following the natural product inspired design approach, a library of (E)-styryl-1H-benzo[d]imidazoles was synthesized and evaluated with recombinant enzyme and on several cancer cell lines. Copyright

Condensation of o-phenylenediamine with cinnamic acids

Condensation of o-phenylenediamine sulfate with cinnamic acids in refluxing ethylene glycol yielded the corresponding 2-styrylbenzimidazoles in excellent yields.