28952-70-7

Basic information

• Product Name: 2-Bromo-N-methyl-2-propen-1-amine
• Synonyms: 2-Bromo-N-methyl-2-propen-1-amine
• CAS NO: 28952-70-7
• Molecular Formula: C4H8BrN
• Molecular Weight: 150.02
• Mol File: 28952-70-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 135 °C
• Appearance: /
• Density: 1.346±0.06 g/cm3(Predicted)
• PKA: 9.56±0.10(Predicted)
• CAS DataBase Reference: 2-Bromo-N-methyl-2-propen-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-N-methyl-2-propen-1-amine(28952-70-7)
• EPA Substance Registry System: 2-Bromo-N-methyl-2-propen-1-amine(28952-70-7)

Safety Data

• Hazardous Substances Data: 28952-70-7(Hazardous Substances Data)

Upstream product

• 74-89-5 methylamine 
• 513-31-5 2-bromoallyl bromide 
• 32777-57-4 N-2-Bromallyl-N-Methyl-p-Toluolsulfonamid 
• 71-43-2 benzene 

Downstream Products

• 32974-37-1 N-2-Bromallyl-N-methyl-N-2,3,4,5,6-pentafluorbenzylamin 
• 89796-25-8 N-Methyl-N-<2-brom-allyl>-1-amino-propanol-(2) 

Relevant articles and documents

Novel arylalkenylpropargylamines as neuroprotective, potent, and selective monoamine oxidase B inhibitors for the treatment of Parkinson's disease

To develop novel neuroprotective agents, a library of novel arylalkenylpropargylamines was synthesized and tested for inhibitory activities against monoamine oxidases. From this, a number of highly potent and selective monoamine oxidase B inhibitors were identified. Selected compounds were also tested for neuroprotection in in vitro studies with PC-12 cells treated with 6-OHDA and rotenone, respectively. It was observed that some of the compounds tested yielded a marked increase in survival in PC-12 cells treated with the neurotoxins. This indicates that these propargylamines are able to confer protection against the effects of the toxins and may also be considered as novel disease-modifying anti-Parkinsonian agents, which are much needed for the therapy of Parkinson's disease.