28957-33-7

Usage

Uses

Used in Plastics Industry:
D-alpha-Amino-epsilon-caprolactam is used as a monomer in the production of plastics for its ability to contribute to the formation of polymers with desirable properties, such as strength and flexibility.
Used in Synthetic Fibers Industry:
In the synthetic fibers industry, D-alpha-Amino-epsilon-caprolactam is used as a precursor for the production of nylon, which is known for its durability and versatility in various applications, including textiles and industrial materials.
Used in Chemical Research:
D-alpha-Amino-epsilon-caprolactam is utilized as a research compound in chemical studies for its unique properties and reactivity, enabling the development of new chemical processes and understanding of molecular interactions.
Used in Molecular Biology:
In molecular biology, D-alpha-Amino-epsilon-caprolactam is employed in the synthesis of biologically active molecules and the study of protein structures, owing to its ability to form stable peptide bonds and participate in various biochemical reactions.

Upstream product

• 6804-88-2 α-nitrocaprolactam 
• 17929-90-7 3-aminoazepan-2-one 

Downstream Products

• 179535-30-9 (R)-3-(Trityl-amino)-azepan-2-one 
• 583028-46-0 [(E)-(R)-1-(3,4-dichlorobenzyl)-3-((R)-2-oxoazepan-3-ylcarbamoyl)allyl]methylcarbamic acid tert-butyl ester 
• 179686-45-4 3-(S)-tert-butoxycarbonylamino-4,5,6,7-tetrahydroazepin-2-one 
• 16851-56-2 indolin-2-yl carboxylic acid 
• 1067658-96-1 tert-butyl methyl((R)-azepan-2-one-3-ylamino-(S)-oxo-3-phenylpropan-2-yl)carbamate 
• 1067659-02-2 tert-butyl methyl((R)-azepan-2-one-3-ylamino-(R)-oxo-3-phenylpropan-2-yl)carbamate 
• 1415251-17-0 C₃₈H₅₇N₉O₈ 
• 124932-43-0 (R)-(+)-3-Amino-hexahydro-1H-azepin 

Relevant academic research and scientific papers

SEPARATING AGENT FOR CHROMATOGRAPHY

A separating agent for chromatography is provided that is useful for the separation of specific compounds, e.g., for the optical resolution of amino acids. This separating agent for chromatography provides a higher productivity and contains a crown ether-like cyclic structure and optically active binaphthyl. This separating agent for chromatography containing a crown ether-like cyclic structure and optically active binaphthyl is provided by introducing a substitution group for binding to carrier into a specific commercially available 1,1′-binaphthyl derivative that has substituents at the 2, 2′, 3, and 3′ positions, then introducing a crown ether-like cyclic structure, and subsequently chemically bonding the binaphthyl derivative to the carrier through the substitution group for binding to carrier.

COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS

The present invention relates to derivatized cyclofructan compounds, compositions comprising derivatized cyclofructan compounds, and methods of using compositions comprising derivatized cyclofructan compounds for chromatographic separations of chemical species, including enantiomers. Said compositions may comprise a solid support and/or polymers comprising derivatized cyclofructan compounds.

Resolution of α-aminolactams by inclusion complexation with chiral host compounds

3-Aminopiperidin-2-one and α-amino-ε-caprolactam were efficiently resolved by inclusion complexation with a chiral host compound, (R,R)-(-)-trans-4,5-bis(hydroxydiphenylmethyl)-1,4-dioxaspiro[4.5]decane . The amino substituent on the lactam ring was found to play an important role in efficient chiral recognition in the inclusion crystals.

Chiral discrimination controlled by the solvent dielectric constant

Chiroselective molecular recognition accompanied by a change in configuration of a target substrate has been studied. (RS)-α-Amino-ε- caprolactam 1 was used as the target substrate to be resolved while N-tosyl-(S)-phenylalanine 2 was used as the chiral selector. The dielectric constant (ε) of the solvent was found to have a profound effect on the chiroselective molecular recognition. The specific chiral selector (S)-2 not only recognized both enantiomers (R)- and (S)-1 individually to be deposited as the less-soluble salt from the different solvent but also controlled the configuration and diastereomeric excess of the less-soluble diastereomeric salt by simple adjustment of the solvents dielectric constant. The chiroselective recognition mechanism was examined based on the crystal structures of the salts, (S)-1·(S)-2·H2O and (R)-1·(S)-2, obtained from the resolution process.