289680-78-0

Upstream product

• 75-05-8 acetonitrile 
• 209391-60-6 [2-chloro-2-(p-tolylsulfinyl)ethene-1,1-diyl]dibenzene 
• 99749-00-5 lithioacetonitrile 

Downstream Products

• 224319-39-5 2-amino-1-cyano-5,5-diphenyl-1,3-cyclopentadiene 
• 625844-85-1 2-amino-3-(4-methoxyphenyl)-5,5-diphenylcyclopenta-1,3-diene-1-carbonitrile 
• 625844-84-0 2-amino-3-ethyl-5,5-diphenylcyclopenta-1,3-diene-1-carbonitrile 
• 625844-83-9 2-amino-3-methyl-5,5-diphenylcyclopenta-1,3-diene-1-carbonitrile 
• 1233484-40-6 C₁₆H₁₂⁽²⁾HN 
• 1365261-19-3 C₁₆H₁₃N 
• 28098-84-2 1-cyano-2,2-diphenylcyclopropane 
• 5195-33-5 3,4-diphenylbut-3-enenitrile 

Relevant academic research and scientific papers

A novel synthesis of 2,4,4-trisubstituted 2-cyclopentenones by consecutive reaction of 1-chlorovinyl p-tolyl sulfoxides with acetonitrile and its homologues

1-Chlorovinyl p-tolyl sulfoxides were synthesized from several kinds of ketones and chloromethyl p-tolyl sulfoxide in three steps in high overall yields. Treatment of the 1-chlorovinyl p-tolyl sulfoxides with cyanomethyllithium (lithium α-carbanion of ace

A novel synthesis, including asymmetric synthesis, of 2,4,4-trisubstituted 2-cyclopentenones based on the reaction of 1-chlorovinyl p-tolyl sulfoxides with acetonitrile and its homologues

Reaction of 1-chlorovinyl p-tolyl sulfoxides, which were synthesized from chloromethyl p-tolyl sulfoxide and ketones in high overall yields, with cyanomethyllithium (lithium α-carbanion of acetonitrile) gave adducts in high to quantitative yields. The add

Reaction of 1-chlorovinyl p-tolyl sulfoxides with carbanion of acetonitrile: A novel synthesis of cyclopentanone derivatives with three consecutive carbon-carbon bond-formations via the enaminonitriles

Treatment of 1-chlorovinyl p-tolyl sulfoxides derived from ketones with cyanomethyllithium gave cyclopentadienyl enaminonitriles in high yields with three consecutive carbon- carbon bond-formations. However, the 1-chlorovinyl p-tolyl sulfoxides derived from aldehydes did not give good results. The mechanism of this reaction and the reaction of the enaminonitriles to convert cyclopentanone derivatives were investigated. Several α-carbanion of nitriles other than acetonitrile added to the 1-chlorovinyl p-tolyl sulfoxides at low temperature in good yield; however, they did not cyclize upon warming to room temperature. (C) 2000 Elsevier Science Ltd.