289688-87-5Relevant articles and documents
Dearomatization of a 3-Hydroxypyridine through an Unexpected Oxidative Deformylation Process: An Entry to Azacyclohexadienones
Mabrouki, Afef,Le Nahenec-Martel, Patricia,Kriaa, Abdelkader,Hedhli, Ahmed,Renard, Pierre-Yves,Sabot, Cyrille
, p. 1497 - 1500 (2020)
Phenols are well-known precursors of cyclohexadienones, which have widespread applications in organic synthesis. In contrast, their hydroxypyridine counterparts have not been explored yet. An unprecedented oxidative dearomatization of a 3-hydroxypyridine involving an unexpected deformylation step is reported. The chemical reactivity of the resulting unreported azacyclohexadiene-type compound was also explored.
PYRIDONE DERIVATIVE HAVING AFFINITY FOR CANNABINOID 2-TYPE RECEPTOR
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Page/Page column 49, (2008/06/13)
It was found that the compound having a binding activity to the cannabinoid type 2 receptor represented by the formula (I): wherein R' is a group represented by the formula: -Y1-Y2-Y3Ra wherein Y1 is single bond or the like; Y2 is -C(=O)-NH- or the like; Y3 is optionally substituted aryl or the like; R2 is hydrogen or the like; R3 is alkyl or the like; R4 is alkyl or the like; R5 is optionally substituted alkyl or the like; or R3 and R4 taken together with the adjacent atom form cyclic group or the like.