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N-(3-{5-[3-(3-dimethylamino-propylamino)-propyl]-9,9-dimethyl-9H-xanthen-4-yl}-propyl)-N',N'-dimethyl-propane-1,3-diamine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

289719-94-4

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289719-94-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 289719-94-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,9,7,1 and 9 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 289719-94:
(8*2)+(7*8)+(6*9)+(5*7)+(4*1)+(3*9)+(2*9)+(1*4)=214
214 % 10 = 4
So 289719-94-4 is a valid CAS Registry Number.

289719-94-4Upstream product

289719-94-4Downstream Products

289719-94-4Relevant academic research and scientific papers

Synthesis and evaluation of 9,9-dimethylxanthene tricyclics against trypanothione reductase, Trypanosoma brucei, Trypanosoma cruzi and Leishmania donovani

Chibale, Kelly,Visser, Mark,Yardley, Vanessa,Croft, Simon L.,Fairlamb, Alan H.

, p. 1147 - 1150 (2000)

Derivatives of 9,9-dimethylxanthene was synthesised and evaluated against trypanothione reductase (TR) and in vitro against parasitic trypanosomes and leishmania. High in vitro antiparasitic activity was observed for some derivatives with one compound showing high activity against all three parasites (ED50 values of 0.02, 0.48 and 0.32 μM, for Trypanosoma brucei, Trypanosoma cruzi, and Leishmania donovani, respectively). The lack of correlation between inhibitory activity against TR and ED50 values suggests that TR is not the target. (C) 2000 Elsevier Science Ltd. All rights reserved.

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