289725-99-1Relevant academic research and scientific papers
Analogs of methyl-piperidinopyrazole (MPP): Antiestrogens with estrogen receptor α selective activity
Zhou, Hai-Bing,Carlson, Kathryn E.,Stossi, Fabio,Katzenellenbogen, Benita S.,Katzenellenbogen, John A.
scheme or table, p. 108 - 110 (2009/05/07)
Methyl-piperidino-pyrazole (MPP), an estrogen receptor α (ERα)-selective antagonist we developed, has a basic side chain (BSC) attached to an ERα-selective agonist ligand, methyl-pyrazole-triol (MPT) through an ether linkage. To remove the possibility tha
Regioselective synthesis of 1,3,5-triaryl-4-alkylpyrazoles: novel ligands for the estrogen receptor.
Huang,Katzenellenbogen
, p. 2833 - 2836 (2007/10/03)
[reaction: see structure] A regioselective synthesis of 4-alkyl-1,3,5-triarylpyrazoles has been developed for the preparation of unsymmetrically substituted systems of interest as ligands for the estrogen receptor.
