2898-76-2 Usage
Uses
Benzamil Hydrochloride is a specific blocker of sodium channels. It also inhibits epithelial sodium channel (ENaC). Benzamil Hydrochloride is an analog of Amiloride (A578700).
Check Digit Verification of cas no
The CAS Registry Mumber 2898-76-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,9 and 8 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2898-76:
(6*2)+(5*8)+(4*9)+(3*8)+(2*7)+(1*6)=132
132 % 10 = 2
So 2898-76-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H14ClN7O.ClH/c14-9-11(16)20-10(15)8(19-9)12(22)21-13(17)18-6-7-4-2-1-3-5-7;/h1-5H,6H2,(H4,15,16,20)(H3,17,18,21,22);1H
2898-76-2Relevant articles and documents
Production of new amilorides as potent inhibitors of mitochondrial respiratory complex I
Murai, Masatoshi,Habu, Sayako,Murakami, Sonomi,Ito, Takeshi,Miyoshi, Hideto
, p. 1061 - 1066 (2015/10/05)
Amilorides, well-known inhibitors of Na+/H+ antiporters, have also shown to inhibit bacterial and mitochondrial NADH-quinone oxidoreductase (complex I). Since the membrane subunits ND2, ND4, and ND5 of bovine mitochondrial complex I