28987-49-7

Upstream product

• 71-23-8 propan-1-ol 
• 394-41-2 3-fluoro-4-nitrophenol 
• 106-94-5 propyl bromide 

Downstream Products

• 113501-99-8 2-nitro-5-propoxyaniline 
• 1446282-02-5 2-chloro-N-(2-nitro-5-propoxyphenyl)acetamide 
• 1446282-03-6 N-(2-nitro-5-propoxyphenyl)-2-piperidylacetamide 
• 1446282-04-7 N-(2-amino-5-propoxyphenyl)-2-piperidylacetamide 
• 1446282-05-8 N-(2-{[2-(2,6-dimethylphenoxy)ethyl]amino}-5-propoxyphenyl)-2-piperidylacetamide 
• 1446281-89-5 1-[2-(2,6-dimethylphenoxy)ethyl]-2-piperidin-1-ylmethyl-5-propoxy-1H-benzimidazole 
• 859877-40-0 N-methyl-2-nitro-5-propoxyaniline 

Relevant academic research and scientific papers

BENZIMIDAZOLE DERIVATIVES AS SELECTIVE BLOCKERS OF PERSISTENT SODIUM CURRENT

The present invention is directed to methods of treating diseases or conditions mediated by elevated persistent sodium channel, such as ocular disorders, pain, multiple sclerosis, and seizure disorders utilizing a compound of Formula I or a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising said compound, wherein variables R, R1, R2, R3, R4, R5, m, and n in Formula I are as defined herein

CYCLIC GUANIDINES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE

The present invention relates to cyclic guanidines, compositions containing such compounds and methods of treatment. The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.