28989-00-6Relevant academic research and scientific papers
Silver-Induced [3+2] Cycloaddition of Isocyanides with Acyl Chlorides: Regioselective Synthesis of 2,5-Disubstituted Oxazoles
Liu, Jian-Quan,Shen, Xuanyu,Shatskiy, Andrey,Zhou, Enlong,K?rk?s, Markus D.,Wang, Xiang-Shan
, p. 4272 - 4275 (2019/07/19)
A silver-induced cycloaddition of isocyanides with acyl chlorides has been developed. This transition metal-catalyzed strategy provides an effective and scalable approach for the formation of 2,5-disubstituted oxazoles in good to high yields. The employed silver-based MOF catalyst can be efficiently recycled without compromising the yield.
