2-Oxazolecarboxylic acid, 5-(phenylmethyl)-, ethyl ester

Base Information

Chemical Name:2-Oxazolecarboxylic acid, 5-(phenylmethyl)-, ethyl ester
CAS No.:28989-00-6
Molecular Formula:C13H13NO3
Molecular Weight:231.251
Hs Code.:
Mol file:28989-00-6.mol

Synonyms:Ethyl-5-benzyloxazolo-2-carboxylat;5-Benzyl-oxazole-2-carboxylic acid ethyl ester;

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Chemical Property of 2-Oxazolecarboxylic acid, 5-(phenylmethyl)-, ethyl ester

Chemical Property:

PSA：52.33000
LogP:2.44210

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 2-Oxazolecarboxylic acid, 5-(phenylmethyl)-, ethyl ester

There total 4 articles about 2-Oxazolecarboxylic acid, 5-(phenylmethyl)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 2999-46-4
Ethyl isocyanoacetate

: 103-80-0
phenylacetyl chloride

: 28989-00-6
5-benzyl-oxazole-2-carboxylic acid ethyl ester

Guidance literature:: With silver based metal organic framework; In 1,4-dioxane; at 80 ℃; regioselective reaction; Inert atmosphere;
DOI:10.1002/cctc.201900965

Reference yield:

: 28988-99-0
(2-oxo-3-phenyl-propyl)-oxalamic acid ethyl ester

: 28989-00-6
5-benzyl-oxazole-2-carboxylic acid ethyl ester

Guidance literature:: With trichlorophosphate; In benzene; for 12h; Heating;
DOI:10.1039/j39700001938

Reference yield:

: 41173-00-6
1-amino-3-phenylpropan-2-one hydrochloride

: 28989-00-6
5-benzyl-oxazole-2-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: benzene

2: POCl₃ / benzene / 12 h / Heating

With trichlorophosphate; In benzene;
DOI:10.1039/j39700001938