289910-01-6Relevant academic research and scientific papers
Syntheses of nucleic acid mimics designed for metal-induced strand formation on DNA
Hatano, Akihiko,Tanaka, Kentaro,Shiro, Motoo,Shionoya, Mitsuhiko
, p. 2965 - 2972 (2007/10/03)
This paper describes design and syntheses of a new class of chelator-type nucleic acid mimics. Four nucleic acid mimics 7, 11, 15, 17 possess a nucleobase and two ethylenediamine moieties for intermolecular metal coordination. We expected that chelator-ty
Self-assembly of chelator-type nucleic acid mimics into a single-stranded ZnII coordination polymer
Hatano, Akihiko,Tanaka, Kentaro,Shiro, Motoo,Shionoya, Mitsuhiko
, p. 822 - 823 (2007/10/03)
The synthesis of a "chelator-type" adenine mimic, which has two metal binding sites, and its ZnII-assisted self-assembly into a single-stranded coordination polymer are described. The UV absorption changes of a 1 : 1 mixture of the ZnII complex and a single-stranded DNA oligomer (dT)70 showed the temperature-dependent hyperchromic effect in an analogous manner as thermal denaturation processes of natural DNA duplexes.
