290306-56-8

Basic information

• Product Name: 2-BROMO-1-(P-TOLUENESULFONYL)PYRROLE 9&
• Synonyms: 2-BROMO-1-(P-TOLUENESULFONYL)PYRROLE 9&;2-Bromo-1-(toluene-4-sulphonyl)-1H-pyrrole;2-Bromo-1-[(4-methylphenyl)sulphonyl]-1H-pyrrole;2-Bromo-1-[(4-methylphenyl)sulphonyl]-1H-pyrrole, 2-Bromo-1-tosyl-1H-pyrrole;2-broMo-1-[(4-Methylphenyl)sulfonyl]-1H-pyrrole;2-Bromo-1-tosyl-1H-pyrrole;2-Bromo-N-(p-toluenesulfonyl)pyrrole（WS204324）
• CAS NO: 290306-56-8
• Molecular Formula: C₁₁H₁₀BrNO₂S
• Molecular Weight: 300.175
• Product Categories: Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyrroles;PyrrolesHeterocyclic Building Blocks;organic building block
• Mol File: 290306-56-8.mol

Chemical Properties

• Melting Point: 102-105 °C(lit.)
• Boiling Point: 426.9°C at 760 mmHg
• Flash Point: 212°C
• Appearance: /
• Density: 1.53g/cm³
• Vapor Pressure: 1.7E-07mmHg at 25°C
• Refractive Index: 1.626
• PKA: -11.62±0.70(Predicted)
• CAS DataBase Reference: 2-BROMO-1-(P-TOLUENESULFONYL)PYRROLE 9&(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-1-(P-TOLUENESULFONYL)PYRROLE 9&(290306-56-8)
• EPA Substance Registry System: 2-BROMO-1-(P-TOLUENESULFONYL)PYRROLE 9&(290306-56-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 290306-56-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-BROMO-1-(P-TOLUENESULFONYL)PYRROLE 9& is used as a key intermediate for the synthesis of various pharmaceuticals due to its ability to facilitate the formation of essential carbon-carbon and carbon-heteroatom bonds in drug molecules.
Used in Agrochemical Industry:
In the agrochemical sector, 2-BROMO-1-(P-TOLUENESULFONYL)PYRROLE 9& is utilized as a reagent in the synthesis of agrochemicals, contributing to the development of new compounds with potential applications in crop protection and pest control.
Used in Medicinal Chemistry Research:
2-BROMO-1-(P-TOLUENESULFONYL)PYRROLE 9& is employed as a research tool in medicinal chemistry, aiding in the exploration of new chemical entities and the optimization of drug candidates through its potential for diverse functionalization.
Used in Material Science:
2-BROMO-1-(P-TOLUENESULFONYL)PYRROLE 9& is also used in material science as a building block for the development of new materials, taking advantage of its unique structural and chemical features to create innovative composites and functional materials.

InChI:InChI=1/C11H10BrNO2S/c1-9-4-6-10(7-5-9)16(14,15)13-8-2-3-11(13)12/h2-8H,1H3

Upstream product

• 38480-28-3 2-bromo-1H-pyrrole 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 637354-45-1 2-(3-nitro-phenyl)-1-(toluene-4-sulfonyl)-1H-pyrrole 
• 153633-36-4 2-phenyl-1-(p-toluenesulfonyl)pyrrole 
• 637354-46-2 2-(4-methoxyphenyl)-1-tosyl-1H-pyrrole 
• 17639-64-4 N-p-toluenesulfonylpyrrole 
• 1239714-95-4 C₁₄H₁₂N₂O₃S 

Relevant articles and documents

S2 emission from chemically modified BODIPYs

Novel boron dipyrromethene (BODIPY) derivatives having significant absorption and emission in the longer wavelength region were synthesized. BODIPY showed anomalous S2 emission from the second excited (S2) state at shorter wavelength

2-Bromo-N-(p-toluenesulfonyl)pyrrole: A Robust Derivative of 2-Bromopyrrole

2-Bromo-AL(p-toluenesulfonyl)pyrrole (2), a crystalline stable derivative of 2-bromopyrrole (1) has been prepared in 80% yield by bromination of pyrrole, followed by conversion to the N-(p-toluenesulfonyl) derivative. This compound is stable indefinitely at ambient temperature. Compound 2 is an excellent substrate for Suzuki coupling with arylboronic acids.

Condensation reactions of a nitrodienamine with organocopper and alkyllithium reagents prepared from pyrrole derivatives

Condensation reactions of a nitrodienamine (1) with Grignard, organocopper and alkyllithium reagents prepared from pyrrole derivatives were investigated.