38480-28-3Relevant articles and documents
Preparation method of vonoprazan intermediate
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Paragraph 0105-0107, (2021/02/10)
The invention provides a preparation method of a vonoprazan intermediate. Specifically, the vonoprazan intermediate is obtained through a bromination reaction, a sulfonylation reaction, a Vilsmeier reaction and a Suzuki reaction. According to the preparation method, dangerous hydrogenation reaction and low-temperature reaction are avoided, and the reaction has the advantages of mild conditions, easiness in operation, cheap raw materials, low production cost and high total yield.
Original design of fluorescent ligands by fusing BODIPY and melatonin neurohormone
Thireau, Jeremy,Marteaux, Justine,Delagrange, Philippe,Lefoulon, Francois,Dufourny, Laurence,Guillaumet, Gerald,Suzenet, Franck
supporting information, p. 158 - 161 (2014/03/21)
An original design and synthesis of fluorescent ligands for melatonin receptor studies is presented and consists in the fusion of the endogenous ligand with the fluorescent BODIPY core. Probes I-IV show high affinities for MT1 and MT2 melatonin receptors and exhibit fluorescence properties compatible with cell observation.
A versatile, modular synthesis of monofunctionalized BODIPY dyes
Leen, Volker,Braeken, Els,Luckermans, Kristof,Jackers, Carine,Van Der Auweraer, Mark,Boens, Noel,Dehaen, Wim
supporting information; experimental part, p. 4515 - 4517 (2010/01/06)
A careful choice of the pyrrole building blocks allows the synthesis of a wide range of monohalogenated BODIPY dyes with excellent reactivity in palladium catalyzed coupling reactions. The Royal Society of Chemistry 2009.
