290346-20-2Relevant academic research and scientific papers
Stereocontrolled backbone connection of peptides by C = C-double bonds
Schumann, Susanne,Zeitler, Kirsten,J?ger, Martin,Polborn, Kurt,Steglich, Wolfgang
, p. 4187 - 4195 (2007/10/03)
Treatment of peptides containing an α-chloroglycine residue with triethylamine and catalytic amounts of triphenylphosphine constitutes an efficient method for the stereoselective synthesis of amino acid and peptide dimers bridged by a C = C-double bond. The dimers can be converted into novel peptide structures by standard methods of peptide synthesis. (C) 2000 Elsevier Science Ltd.
