290818-03-0

Upstream product

• 90288-80-5 2-Isopropyl-2-trimethylsilanyloxy-cyclopropanecarboxylic acid methyl ester 
• 4622-38-2 2-iodobenzyliodide 
• 916977-15-6 methyl 1-(2-iodobenzyl)-2-isopropyl-2-trimethylsiloxycyclopropanecarboxylate 

Downstream Products

• 224568-48-3 methyl 5-methyl-4-oxo-2-(2-trimehylsilylethynylbenzyl)hexanoate 
• 1190211-42-7 methyl 2-(2-isopropenylbenzyl)-5-methyl-4-oxohexanoate 
• 1260498-96-1 methyl 3-{2-[(1Z)-propen-1-yl]phenyl}propanoate 
• 1190211-43-8 methyl 5-methyl-4-oxo-2-[2-(1-phenylethenyl)benzyl]hexanoate 
• 1190211-49-4 methyl 5-methyl-4-oxo-2-{2-[2-phenyl-(1E)-ethennyl]benzyl}hexanoate 
• 1190211-45-0 methyl 5-methyl-4-oxo-2-{2-[(1E)-propen-1-yl]benzyl}hexanoate 
• 1260498-94-9 methyl 5-methyl-4-oxo-2-{2-[(1Z)-propen-1-yl]benzyl}hexanoate 
• 1190211-65-4 methyl 3-{2-[(E)-2-cyclopropylvinyl]phenyl}propanoate 
• 1190211-47-2 methyl 2-{2-[(1E)-cyclopropylvinyl]benzyl}-5-methyl-4-oxohexanoate 
• 224568-42-7 methyl 5-methyl-4-oxo-2-(2-ethynylbenzyl)hexanoate 
• 224568-40-5 methyl 5-methyl-4-oxo-2-(2-vinylbenzyl)hexanoate 
• 290818-09-6 methyl 2-[2-(3-methoxyprop-1-ynyl)benzyl]-5-methyl-4-oxohexanoate 
• 290818-08-5 methyl 2-(2-hex-1-ynylbenzyl)-5-methyl-4-oxohexanoate 

Relevant academic research and scientific papers

Stereoselective synthesis of tricyclic compounds by intramolecular palladium-catalyzed addition of aryl iodides to carbonyl groups

Starting fromγ-ketoesters with an o-iodobenzyl group we studied a palladium-catalyzed cyclization process that stereoselectively led to bi- and tricyclic compounds in moderate to excellent yields. Four X-ray crystal structure analyses unequivocally define

Benzannulated cyclooctanol derivatives by samarium diiodide induced intramolecular carbonyl-alkene coupling - Scope, limitations, stereoselectivity

A series of γ-oxo esters 27-34 was prepared from methyl 2-silyloxycyclopropanecarboxylates 1-9 as key building blocks in a flexible modular synthesis. Their samarium diiodide promoted cyclization to benzannulated cyclooctanol derivatives was systematicall

Competition between novel 8-endo-dig and 6-trig cyclizations of samarium ketyls leading either to benzannulated cyclooctene or to hexahydronaphthalene derivatives

Ketoesters 3a-3h with an alkynylaryl substituent were prepared by standard methods starting from siloxycyclopropanes 6a and 6b. Their reactions with 2.2 equiv. of samarium diiodide in the presence of hexamethyl phosphoramide either produced benzannulated