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Piperazine, 1-[3-[2-(4-bromophenyl)-5-methyl-1H-indol-3-yl]-1-oxopropyl]-4-(2-meth oxyphenyl)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

290830-49-8

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290830-49-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 290830-49-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,9,0,8,3 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 290830-49:
(8*2)+(7*9)+(6*0)+(5*8)+(4*3)+(3*0)+(2*4)+(1*9)=148
148 % 10 = 8
So 290830-49-8 is a valid CAS Registry Number.

290830-49-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-{3-[2-(4-bromophenyl)-5-methyl-1H-indol-3-yl]-1-oxopropyl}-4-(2-methoxyphenyl)piperazine

1.2 Other means of identification

Product number -
Other names 3-[2-(4-Bromo-phenyl)-5-methyl-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:290830-49-8 SDS

290830-49-8Downstream Products

290830-49-8Relevant academic research and scientific papers

2-aryl indole derivative as antagonists of tachykinins

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Page/Page column 32, (2008/06/13)

The present invention relates to compounds of the formula (I): wherein R1a, R1b, R2, R3, R4, R5, X and n are defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis and postherpetic neuralgia.

2-Aryl indole NK1 receptor antagonists: Optimisation of the 2-aryl ring and the indole nitrogen substituent

Dinnell, Kevin,Chicchi, Gary G.,Dhar, Madhumeeta J.,Elliott, Jason M.,Hollingworth, Gregory J.,Kurtz, Marc M.,Ridgill, Mark P.,Rycroft, Wayne,Tsao, Kwei-Lan,Williams, Angela R.,Swain, Christopher J.

, p. 1237 - 1240 (2007/10/03)

Novel 2-aryl indole hNK1 receptor ligands were prepared utilising palladium cross-coupling chemistry of a late intermediate as a key step. Compounds with high hNK1 receptor binding affinity and good brain penetration (e.g., 9d) were synthesised.

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