2909-84-4

Usage

Uses

Used in Chemical Synthesis Industry:
2,4-DI-TERT-BUTYLANILINE is used as an intermediate for the production of dyes and pigments, contributing to the coloration and stability of these substances in various applications.
Used in Polymer Composites Industry:
It serves as a stabilizer in the production of polymer composites, enhancing the stability and performance of these materials in diverse industrial applications.
Used in Pharmaceutical Industry:
2,4-DI-TERT-BUTYLANILINE is utilized as an intermediate in the synthesis of pharmaceuticals, playing a crucial role in the development of new drugs and medicinal compounds.
Used in Agrochemical Industry:
2,4-DI-TERT-BUTYLANILINE is also employed as an intermediate in the creation of agrochemicals, aiding in the production of substances that protect and enhance crop yields and quality.

Upstream product

• 93720-37-7 2,4-di-tert-butyl-1-nitrobenzene 
• 80438-69-3 3,5-di(tert-butyl)-2-nitro-1-bromobenzene 
• 80438-68-2 1-chloro-2-nitro-3,5-di-tert-butylbenzene 
• 60190-51-4 3,5-di-tert-butyl-2-nitroaniline 
• 22385-77-9 1-bromo-3,5-di-tert-butylbenzene 
• 1014-60-4 1,3-di-tert-butylbenzene 
• 62-53-3 aniline 
• 75-65-0 tert-butyl alcohol 
• 1460-02-2 1,3,5-Tri-tert-butylbenzene 
• 96-76-4 2,4-di-tert-Butylphenol 
• 1071592-60-3 2,4-di-tert-butylphenyl trifluoromethanesulfonate 

Downstream Products

• 101355-80-0 2,4-Di-tert-butylformanilid 
• 76663-08-6 2-(2,4-Di-tert-butyl-phenylamino)-N-(4-sulfamoyl-phenyl)-acetamide 
• 80438-54-6 2-bromo-4,6-di-tert-butylaniline 
• 91787-14-3 2-iodo-4,6-di-tert-butylaniline 
• 83054-79-9 2,9-Bis-(2,4-di-tert-butyl-phenyl)-anthra[2,1,9-def;6,5,10-d'e'f']diisoquinoline-1,3,8,10-tetraone 
• 538315-29-6 (2E,4E,6E)-7-(2,4-Di-tert-butyl-phenylcarbamoyl)-3-methyl-octa-2,4,6-trienoic acid methyl ester 
• 860305-61-9 N-sulfinyl-2,4-di-tert-butylaniline 
• 921626-13-3 N-(2,4-Di-tert-butyl-phenyl)-2-[(E)-hydroxyimino]-acetamide 
• 1620642-92-3 C₃₇H₅₂AlN₃ 
• 76662-62-9 2-[Acetyl-(2,4-di-tert-butyl-phenyl)-amino]-N-(4-sulfamoyl-phenyl)-acetamide 

Relevant academic research and scientific papers

Tertiary butylation of aniline over nanosized zeolite beta catalyst

In the current paper, we report nanosized zeolite beta to be a robust and potent catalyst for tertbutylation of aniline. Nanocrystals of beta zeolite having spherical morphology were prepared via a one-pot strategy that is based on vacuum-concentration coupled hydrothermal method. The catalyst could be used in the as-synthesized form, without any further modifications. In the presence of the as-prepared catalyst, liquid-phase tert-butylation of aniline using tert-butanol as alkylating agent proceeded successfully. Reaction parameters like duration of reaction, temperature, mole ratio of substrates and quantity of catalyst were optimized. Time-dependent data obtained was subjected to kinetic studies. Detailed studies on product selectivity were conducted. The catalyst could selectively direct the formation of C–C bonds and no N-alkylated products were detected. It also demonstrated good selectivity towards mono-substitution. The catalyst could be recovered by a simple work-up plan and could then be re-used. No appreciable loss in activity was detected in consecutive runs. Thus, the nanosized beta mediated route to introduce tert-butyl group on aniline ring can be an environment-friendly alternative to the use of homogeneous catalysts.

Atroposelective sp3 C—H Coupling for Kinetic Resolution of Thioanilide Atropisomers

A highly efficient kinetic resolution of racemic thioanilide atropisomers via C(sp3)?H arylation has been achieved by a hybrid palladium catalyst bearing an anionic chiral CoIII-complex and a phosphoramidite ligand, leading to both e

A Metal-Free Direct Arene C?H Amination

The synthesis of aryl amines via the formation of a C?N bond is an essential tool for the preparation of functional materials, active pharmaceutical ingredients and bioactive products. Usually, this chemical connection is only possible by transition metal-catalyzed reactions, photochemistry or electrochemistry. Here, we report a metal-free arene C?H amination using hydroxylamine derivatives under benign conditions. A charge transfer interaction between the aminating reagents TsONHR and the arene substrates enables the chemoselective amination of the arene, even in the presence of various functional groups. Oxygen was crucial for an effective conversion and its accelerating role for the electron transfer step was proven experimentally. In addition, this was rationalized by a theoretical study which indicated the involvement of a dioxygen-bridged complex with a “Sandwich-like” arrangement of the aromatic starting materials and the aminating agents at the dioxygen molecule. (Figure presented.).

Atropisomerism in Diarylamines: Structural Requirements and Mechanisms of Conformational Interconversion

In common with other hindered structures containing two aromatic rings linked by a short tether, diarylamines may exhibit atropisomerism (chirality due to restricted rotation). Previous examples have principally been tertiary amines, especially those with

Electrochemical Amination of Less-Activated Alkylated Arenes Using Boron-Doped Diamond Anodes

The anodic C-H amination of aromatic compounds is a powerful and versatile method for the synthesis of aniline derivatives. By using boron-doped diamond (BDD) anodes, a method initially described by Yoshida et al. for electron-rich arenes was expanded to less-activated aromatic systems e.g., simple alkylated benzene derivatives. Anodes based on sp3 carbon seem to be the key for the electrochemical amination reaction. The corresponding primary anilines are obtained in good yields. Despite the cationic intermediates of the electrolytic reaction tert-butyl moieties are tolerated.

Derivatives of m-di-tert-butylbenzene. Part VI. The preparation of miscellaneous halogenated compounds

The preparation of seven series of dihalogenated and monohalogenated derivatives of m-di-tert-butylbenzene, comprising twenty three new compounds, is described.

Chemical process for forming 2,6-dimethylaniline

Hydroxy aromatics are aminated to form the corresponding aromatic amine by reaction at 200°-400°C with ammonia in the presence of a cyclohexanone and water in contact with a hydrogen transfer catalyst. For example, 2,6-dimethylphenol reacts with ammonia in the presence of cyclohexanone, water and a supported palladium catalyst to form 2,6-dimethylaniline.