29111-73-7

Usage

Uses

Used in Chemical Industry:
4-(N-Acetyl)amino-3-nitrotoluene is used as an intermediate substance for the production of dyes and pigments, contributing to the coloration and appearance of various products. Its stability and heat resistance make it a preferred choice in the chemical industry for these applications.
Used in Research and Development:
In the field of research and development, 4-(N-Acetyl)amino-3-nitrotoluene is utilized as a key component in various chemical reactions, allowing scientists to explore new compounds and materials. Its unique properties facilitate the synthesis of novel substances with potential applications in different industries.
Used in Industrial Applications:
Due to its high stability and good heat resistance, 4-(N-Acetyl)amino-3-nitrotoluene is employed in various industrial applications where these properties are essential. Its use in these settings helps to improve the performance and durability of the final products.

InChI:InChI=1/C9H10N2O4/c1-6-3-4-7(10-9(12)15-2)8(5-6)11(13)14/h3-5H,1-2H3,(H,10,12)

Upstream product

• 79-22-1 methyl chloroformate 
• 89-62-3 4-methyl-2-nitroaniline 
• 5602-96-0 methyl p-tolylcarbamate 

Downstream Products

• 1221498-26-5 methyl allyl(4-methyl-2-nitrophenyl)carbamate 

Relevant academic research and scientific papers

The first intramolecular Heck-Matsuda reaction and its application in the syntheses of benzofurans and indoles

In this Letter, we report, for the first time, the development of an efficient method for the intramolecular Heck reaction of arenediazonium salts in the synthesis of benzofuran and indole derivatives. In addition, this methodology allowed the synthesis of a series of dihydrobenzofuran acetic acid derivatives via a domino Heck-Matsuda coupling-carbonylation reaction.

Synthesis of alkyl N-(C-nitrosoaryl)carbamates and some reactions thereof

Reactions of alkyl N-phenylcarbamates, m-di(methoxycarboxyamido)benzene, and methyl N-(o-tolyl)carbamate with nitrosylsulfuric acid in glacial acetic acid afford N-(C-nitrosoaryl)carbamates; under these conditions tert-bulyl N-phenylcarbamate suffers decarboxylation, methyl N-(p-tolyl)-, methyl N-(p-methoxyphenyl)carbamates, o-and p-di(methoxycarboxyamido)benzenes are nitrated, and isomeric methyl N-nitrophenylcarbamates and methyl N-(p-bromophenyl)carbamate do not react. The reduction of N-(C-nitrosoaryl)carbamates with dithionite afforded the corresponding aminocarbamates; the oxidation with nitric acid yielded carbamate nitro derivatives; the condensation with aniline and benzylpyridinium chloride resulted in carbamate derivatives of azobenzene and phenylnitron.