2912-76-7

Basic information

• Product Name: 2-HYDROXY-3-NITROBENZAMIDE
• Synonyms: 2-HYDROXY-3-NITROBENZAMIDE
• CAS NO: 2912-76-7
• Molecular Formula: C₇H₆N₂O₄
• Molecular Weight: 182.134
• Mol File: 2912-76-7.mol

Chemical Properties

• Boiling Point: 283.1°C at 760 mmHg
• Flash Point: 125°C
• Appearance: /
• Density: 1.538g/cm³
• Vapor Pressure: 0.00189mmHg at 25°C
• Refractive Index: 1.658
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-HYDROXY-3-NITROBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDROXY-3-NITROBENZAMIDE(2912-76-7)
• EPA Substance Registry System: 2-HYDROXY-3-NITROBENZAMIDE(2912-76-7)

Safety Data

• Hazardous Substances Data: 2912-76-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
2-HYDROXY-3-NITROBENZAMIDE is used as a research compound for investigating its potential as an anti-tumor agent. Its biological activities have been of interest in the development of new drugs and therapies.
Used in Organic Synthesis:
2-HYDROXY-3-NITROBENZAMIDE is used as an intermediate in the production of various chemicals and pharmaceuticals. Its unique molecular structure and reactivity make it a valuable component in the synthesis of complex organic molecules.
Used in Chemical Production:
2-HYDROXY-3-NITROBENZAMIDE is utilized as a key intermediate in the manufacturing process of specific chemicals, contributing to the development of new materials and compounds with diverse applications across industries.

InChI:InChI=1/C7H6N2O4/c8-7(11)4-2-1-3-5(6(4)10)9(12)13/h1-3,10H,(H2,8,11)

Upstream product

• 90564-38-8 2-Hydroxy-3-nitrobenzoesaeureethylester 
• 7664-41-7 ammonia 
• 22621-41-6 2-hydroxy-3-nitro-benzoic acid methyl ester 
• 65-45-2 salicylamide 

Downstream Products

• 860000-95-9 2-hydroxy-3-nitro-benzoic acid-(2,2,2-trichloro-1-hydroxy-ethylamide) 
• 467231-62-5 3-amino-2-hydroxybenzamide 
• 1609394-04-8 3-amino-2-(difluoromethoxy)benzamide 
• 1609394-03-7 2-(difluoromethoxy)-3-nitrobenzamide 

Relevant articles and documents

Preparation of new cyclic quaterbenzoxazole and -imidazole derivatives

The new cyclic quaterbenzoxazole 5 and -imidazole 8 have been synthesized by cyclization of 3-amino-2-hydroxybenzamide (4) and the ammonium salt of 2,3-diaminobenzoic acid (7), respectively, with polyphosphoric acid. Both compounds represent a new heteroc

ALKYL-AMIDE-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFNα RESPONSES

Compounds having the following formula (I): or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.

AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHα RESPONSES

Compounds having the following formula I: or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNa, by acting on Tyk-2 to cause signal transduction inhibition.

Clay supported ammonium nitrate "clayan": A new reagent for selective nitration of arenes

The nitration of activated, deactivated and highly functionalized arenes is described using clay-supported ammonium nitrate in the presence of perchloric acid.