29125-48-2 Usage
General Description
2,6-DIMETHYL-4-HYDRAZINOQUINOLINE is a chemical compound with the molecular formula C11H13N3. It is a heterocyclic aromatic compound that contains a quinoline ring system with a dimethyl substitution at the 2 and 6 positions and a hydrazino group attached to the 4 position. 2,6-DIMETHYL-4-HYDRAZINOQUINOLINE is commonly used as a reagent in organic synthesis to introduce the quinoline moiety into various chemical compounds. It also has potential applications in the pharmaceutical industry, where it can be used as a building block to synthesize biologically active molecules or as a fluorescent reagent in biochemical assays. Additionally, 2,6-DIMETHYL-4-HYDRAZINOQUINOLINE has been studied for its potential anticancer and antiviral activities.
Check Digit Verification of cas no
The CAS Registry Mumber 29125-48-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,1,2 and 5 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 29125-48:
(7*2)+(6*9)+(5*1)+(4*2)+(3*5)+(2*4)+(1*8)=112
112 % 10 = 2
So 29125-48-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H13N3/c1-7-3-4-10-9(5-7)11(14-12)6-8(2)13-10/h3-6H,12H2,1-2H3,(H,13,14)
29125-48-2Relevant articles and documents
N1-{4-[(10S)-Dihydroartemisinin-10-oxyl]}phenylmethylene-N 2-(2-methylquinoline-4-yl)hydrazine derivatives as antiplasmodial falcipain-2 inhibitors
Luo, Wei,Liu, Yang,Wang, Jian,Guo, Chun,Lu, Wei-Qiang,Cui, Kun-Qiang
, p. 3073 - 3079,7 (2020/08/20)
A series of N1-{4-[(10S)-dihydroartemisinin- 10-oxyl]}phenylmethylene-N2-(2-methylquinoline-4-yl) hydrazine derivatives 9a-9n possessing 4-quinolylhydrazone and artemisinin cores were herein synthesized and evaluated for their activities against cysteine protease falcipain- 2 of Plasmodium falciparum. The structures were clearly confirmed by elemental analysis, 1H NMR, and mass spectra. The pharmacological results indicated that all compounds showed excellent activity against recombinant falcipain-2 (IC50 = 0.15-2.28 μM). The best one of this series was compound 9d (IC50 = 0.15 μM). The molecular docking results showed that the compound 9d made close contact with the key active site of cysteine protease falcipain-2.
