291276-26-1Relevant academic research and scientific papers
Methaqualone derivatives are potent noncompetitive AMPA receptor antagonists
Chenard,Menniti,Pagnozzi,Shenk,Ewing,Welch
, p. 1203 - 1205 (2000)
Quinazolin-4-one derivatives of methaqualone substituted at C-2 define new class of noncompetitive antagonists at AMPA receptors. (C) 2000 Elsevier Science Ltd. All rights reserved.
Quinazolin-4-one α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists: Structure-activity relationship of the C-2 side chain tether
Chenard,Welch,Blake,Butler,Reinhold,Ewing,Menniti,Pagnozzi
, p. 1710 - 1717 (2007/10/03)
A series of 6-fluoro-3-(2-chlorophenyl)quinazolin-4-ones has been prepared, which contains a 2-fluorophenyl ring attached to C-2 by a variety of two-atom tethers. These compounds were used to probe the structure-activity relationship (SAR) for AMPA recept
Methods of preparing substituted 3-phenyl and 3-pyridyl-4(3H)-quinazolinones and atropisomers thereof
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, (2008/06/13)
This invention is directed to methods for the preparation of quinazolin-4-one derivatives of the formula*(formula 02)*and the pharmaceutically acceptable salts and atropisomers of the formula*(formula 03)*and the pharmaceutically acceptable salts thereof,
