2913-45-3

Usage

Uses

Used in Organic Chemistry:
2,5-Cyclohexadiene-1,4-dione, 3-methoxy-2,5-dimethylis used as a building block in the synthesis of various organic compounds due to its reactive nature and structural features.
Used in Pharmaceutical Production:
2,5-Cyclohexadiene-1,4-dione, 3-methoxy-2,5-dimethylis used as a starting material in the production of pharmaceuticals, leveraging its chemical properties to contribute to the development of new drugs.
Used in Antioxidant Applications:
2,5-Cyclohexadiene-1,4-dione, 3-methoxy-2,5-dimethylis utilized for its antioxidant properties, which can be beneficial in stabilizing formulations and protecting against oxidative damage in various chemical and biological systems.
Used in Material Development:
2,5-Cyclohexadiene-1,4-dione, 3-methoxy-2,5-dimethylis studied for its potential in the development of new materials, where its unique properties may contribute to the creation of innovative products with enhanced characteristics.
Used in Biological Research:
2,5-Cyclohexadiene-1,4-dione, 3-methoxy-2,5-dimethylis employed in biological research to explore its interactions with biological systems and its potential applications in medicine and biotechnology.

Upstream product

• 56410-34-5 2,4-O-dimethyl-β-orcinolcarboxylic acid 
• 2913-41-9 3-hydroxy-2,5-dimethyl-[1,4]benzoquinone 
• 77-78-1 dimethyl sulfate 
• 53887-75-5 2,4-dimethoxy-3,6-dimethylphenol 
• 29769-77-5 3-methoxy-4-methyl-3-cyclobutene-1,2-dione 
• 74-99-7 prop-1-yne 
• 186581-53-3 diazomethane 
• 19676-67-6 2,4-dimethoxy-3-methylphenol 
• 85071-58-5 2-hydroxy-3,5-dimethoxy-4-methylbenzaldehyde 
• 92421-46-0 3,6-dimethyl-1,2,4-trimethoxybenzene 
• 40853-36-9 2,5-dimethyl-3,4-di-acetoxyphenyl acetate 
• 137-18-8 2,5-Dimethyl-1,4-benzoquinone 

Downstream Products

• 99892-95-2 2-methoxy-3,6-dimethylhydroquinone 
• 1270932-01-8 3,6-dimethyl-2-methoxy-5-hydroxydecyl-p-benzo-quinone 
• 1431987-17-5 8-(4-methoxy-2,5-dimethyl-3,6-dioxocyclohexa-1,4-dienyl)octyl nitrate 
• 1431987-14-2 6-(4-methoxy-2,5-dimethyl-3,6-dioxocyclohexa-1,4-dienyl)hexyl nitrate 
• 1431987-15-3 10-(4-methoxy-2,5-dimethyl-3,6-dioxocyclohexa-1,4-dienyl)decyl nitrate 
• 1594439-39-0 6,6'-(10,10'-(ethane-1,2-diylbis(methylazanediyl))bis(decane-10,1-diyl))bis(3-methoxy-2,5-dimethylcyclohexa-2,5-diene-1,4-dione) 
• 1594439-41-4 2-(10-(4-(biphenylcarbonyl)-1,4-diazepan-1-yl)decyl)-5-methoxy-3,6-dimethylcyclohexa-2,5-diene-1,4-dione 
• 1594439-45-8 2-(10-(4-(biphenylcarbonyl)piperazin-1-yl)decyl)-5-methoxy-3,6-dimethylcyclohexa-2,5-diene-1,4-dione 
• 1594439-31-2 6,6'-(10,10'-(piperazine-1,4-diyl)bis(decane-10,1-diyl))bis(3-methoxy-2,5-dimethylcyclohexa-2,5-diene-1,4-dione) 
• 1594439-35-6 6,6'-(10,10'-(1,4-diazepane-1,4-diyl)bis(decane-10,1-diyl))bis(3-methoxy-2,5-dimethylcyclohexa-2,5-diene-1,4-dione) 
• 1594439-46-9 2-(10-bromodecyl)-5-methoxy-3,6-dimethylcyclohexa-2,5-diene-1,4-dione 
• 1594439-47-0 2-(5-bromopentyl)-5-methoxy-3,6-dimethylcyclohexa-2,5-diene-1,4-dione 
• 1594439-38-9 6,6'-(5,5'-(1,4-diazepane-1,4-diyl)bis(pentane-5,1-diyl))bis(3-methoxy-2,5-dimethylcyclohexa-2,5-diene-1,4-dione) 
• 1608464-08-9 2-(10-(4-((S)-3-(2-((S)-3-(biphenyl-4-yl)-2-hydroxypropoxy)ethoxy)-2-hydroxypropyl)-1H-1,2,3-triazol-1-yl)decyl)-5-methoxy-3,6-dimethylcyclohexa-2,5-diene-1,4-dione 

Relevant academic research and scientific papers

QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS FOR OPHTHALMIC USE

The present invention relates to novel nitric oxide donor compounds for the use in the treatment and/or prophylaxis of hypertensive glaucoma, normotensive glaucoma and ocular hypertension.

Identification of novel bivalent mimetics of annonaceous acetogenins via a scaffold-hopping strategy

A series of novel bivalent mimetics of annonaceous acetogenins have been designed, synthesized, and evaluated. Among these, compound 7 bearing a homopiperazine ring in the middle region exhibited more potent growth inhibitory activity and higher selectivity against cancer cells over normal cells by comparison with AA005. This work indicates that modification of the middle piperazine ring is a useful optimizing tool for the simplified acetogenin mimetics.

Biological evaluation of new mimetics of annonaceous acetogenins: Alteration of right scaffold by click linkage with aromatic functionalities

A small library of analogues of annonaceous acetogenins through click linkage with aromatic moieties is established using a convergent modular fragment-assembly approach. These analogues exhibited low micromolar inhibitory activities against the proliferation of several human cancer cell lines. Structure-activity relationship (SAR) of these analogues indicates that replacement of the methoxy groups of ubiquinone ring with methyl groups is proved to be a useful strategy for improving the anticancer activity of quinone-acetogenin hybrids.

QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS

The present invention relates to nitric oxide donor compounds having a quinone based structure, to processes for their preparation and to their use in the treatment of pathological conditions where a deficit of NO plays an important role in their pathogenesis.

Synthesis and characterization of mitoQ and idebenone analogues as mediators of oxygen consumption in mitochondria

Analogues of mitoQ and idebenone were synthesized to define the structural elements that support oxygen consumption in the mitochondrial respiratory chain. Eight analogues were prepared and fully characterized, then evaluated for their ability to support oxygen consumption in the mitochondrial respiratory chain. While oxygen consumption was strongly inhibited by mitoQ analogues 2-4 in a chain length-dependent manner, modification of idebenone by replacement of the quinone methoxy groups by methyl groups (analogues 6-8) reduced, but did not eliminate, oxygen consumption. Idebenone analogues 6-8 also displayed significant cytoprotective properties toward cultured mammalian cells in which glutathione had been depleted by treatment with diethyl maleate.