85071-58-5

Upstream product

• 19676-67-6 2,4-dimethoxy-3-methylphenol 
• 100-97-0 hexamethylenetetramine 
• 7149-92-0 2,4-dimethoxy-3-methylbenzaldehyde 
• 5673-07-4 2,6-dimethoxytoluene 
• 50-00-0 formaldehyd 

Downstream Products

• 113296-71-2 2-benzyloxy-3,5-dimethoxy-4-methylbenzaldehyde 
• 853995-97-8 2-bromo-6-hydroxy-3,5-dimethoxy-4-methyl-benzaldehyde 
• 113727-24-5 4-methyl-6-nitro-2,3,5-trimethoxybenzaldehyde 
• 113727-25-6 2-Amino-3,5,6-trimethoxy-4-methylbenzaldehyd 
• 113727-26-7 2,3,5-trimethoxy-4-methyl-6-nitrobenzenemethanol 
• 113727-29-0 (+/-)-2-(2-Amino-3,5,6-trimethoxy-4-methylbenzyloxy)-3,4,5,6-tetrahydro-2H-pyran 
• 113727-31-4 N-(2-Brommethyl-3,4,6-trimethoxy-5-methylphenyl)succinimid 
• 113727-27-8 2,3,5-Trimethoxy-4-methyl-6-nitrobenzyl-acetat 
• 113727-28-9 (+/-)-3,4,5,6-Tetrahydro-2-<(2,3,5-trimethoxy-4-methyl-6-nitro)benzyloxy>-2H-pyran 
• 113727-30-3 (+/-)-N-<2,4,5-Trimethoxy-3-methyl-6-(3,4,5,6-tetrahydro-2H-pyran-2-yloxymethyl)phenyl>succinimid 
• 113727-32-5 <2-(2,5-Dioxo-1-pyrrolidinyl)-3,5,6-trimethoxy-4-methylbenzyl>-triphenylphosphoniumbromid 
• 85071-59-6 1-bromo-2,3,5-trimethoxy-4-methylbenzaldehyde 
• 1070888-05-9 2-(2-hydroxy-3,5-dimethoxy-4-methylphenyl)-3-methyl-6-phenethyltetrahydropyran-4-ol 
• 271578-78-0 1,3,4-trimethoxy-2-methyl-5-vinylbenzene 

Relevant academic research and scientific papers

Broadly Applicable Stereoselective Syntheses of Serrulatane, Amphilectane Diterpenes, and Their Diastereoisomeric Congeners Using Asymmetric Hydrovinylation for Absolute Stereochemical Control

A stereogenic center, placed at an exocyclic location next to a chiral carbon in a ring to which it is attached, is a ubiquitous structural motif seen in many bioactive natural products, including di- and triterpenes and steroids. Installation of these ce

New Drug Delivery System for Crossing the Blood Brain Barrier

New ubiquinol analogs are disclosed, as well as methods of using these compounds to deliver drug moieties to the body.

Rapid stereocontrolled assembly of the fully substituted C-aryl glycoside of kendomycin with a Prins cyclization: A formal synthesis

Prins cyclization using an electron-rich benzaldehyde and a homoallylic alcohol efficiently delivered the fully substituted C-aryl tetrahydropyranoside of kendomycin. The Royal Society of Chemistry 2006.

Evolution of a total synthesis of (-)-kendomycin exploiting a Petasis-Ferrier rearrangement/ring-closing olefin metathesis strategy

A convergent stereocontrolled total synthesis of (-)-kendomycin (1) has been achieved. The synthesis proceeds with a longest linear sequence of 21 steps, beginning with commercially available 2,4-dimethoxy-3-methylbenzaldehyde (12). Highlights of the synthesis include an effective Petasis-Ferrier union/rearrangement tactic to construct the sterically encumbered tetrahydropyran ring, a ring-closing metathesis to generate the C(4a-13-20a) macrocycle, an effective epoxidation/deoxygenation sequence to isomerize the C(13,14) olefin, and a biomimetic quinone-methide-lactol assembly to complete the synthesis.