291301-33-2Relevant articles and documents
An α-aminomethyl carbanion equivalent via a novel Barbier reaction: (1H-naphtho[ 1,8-de]-1,2,3-triazin-2-yl)methyl anion
Chandrasekhar, Sosale,Sridhar, Malayalam
, p. 4685 - 4688 (2000)
A novel sonication-promoted Barbier reaction putatively generated the titled species from the corresponding naphthotriazinylmethyl chloride and magnesium in THF: its formal addition to a variety of carbonyl compounds in situ occurred in excellent yields. Subsequent catalytic hydrogenolysis of the triazine moiety demasked the amine, thus defining a route to various phenylethylamines (including the alkaloid 'mescaline'), or ethanolamines (in two cases), in excellent overall yields. (C) 2000 Elsevier Science Ltd.