29138-80-5

Upstream product

• 2403-55-6 4-(2-methyl-1-propenyl)morpholine 
• 1794-48-5 1-bromo-3-phenylprop-2-yne 
• 57187-82-3 (3-((2-methylallyl)oxy)prop-1-yn-1-yl)benzene 
• 1027087-72-4 (3-(2-methylprop-1-enyloxy)prop-1-ynyl)benzene 
• 536-74-3 phenylacetylene 
• 1504-58-1 3-Phenyl-2-propyn-1-ol 

Downstream Products

• 552425-19-1 4,4-dimethyl-5-phenylhepta-5,6-dien-3-ol 
• 552425-12-4 3,3-dimethyl-4-phenylhexa-4,5-dien-2-ol 
• 552425-45-3 4,4-dimethyl-3-phenyl-5-(triethylsiloxy)hepta-1,2,5-triene 
• 1414362-65-4 C₂₄H₃₀N₂ 
• 1414362-83-6 C₂₀H₂₀N₂ 
• 1414363-01-1 C₁₆H₂₀N₂ 
• 1414363-02-2 C₁₇H₂₂N₂ 
• 1414363-03-3 C₁₇H₂₂N₂ 
• 862591-84-2 C₂₆H₂₈N₂ 
• 552425-39-5 2-triethylsilyloxy-3,3-dimethyl-4-phenylhexa-1,4,5-triene 
• 552425-29-3 4,4-dimethyl-5-phenylhepta-5,6-dien-3-one 
• 552425-24-8 3,3-dimethyl-4-phenylhexa-4,5-dien-2-one 
• 174578-98-4 2,2-dimethyl-3-phenylcyclohex-3-en-1-one 
• 851512-75-9 (Z)-4,4-dimethyl-3-phenyl-5-(triethylsiloxy)hepta-1,2,5-triene 

Relevant academic research and scientific papers

Substituted homoallenyl aldehydes and their derivatives. Part 1: Homoallenyl aldehydes and protected hydrazones

The paper presents a simple synthesis of substituted propargyl vinyl ethers and their subsequent thermally-initiated Claisen rearrangement leading to various 3-substituted homoallenyl aldehydes. Several methods, including Sonogashira coupling, base-promoted substitution on the triple bond by sodium amide or butyllithium, and the preparation of substituted propargyl alcohols, were used in the initial step. Phosphate-protected homoallenyl aldehyde hydrazone derivatives were synthesised and fully characterised. The stereochemistry of 9-anthracene carbaldehyde hydrazone, which, surprisingly, afforded both cis and trans isomers, was established using X-ray analysis.

Cationic rhodium(I)-dppf complex-catalyzed olefin isomerization/propargyl claisen rearrangement/carbonyl migration cascade

(Chemical Equation Presented) We have established that a cationic rhodium(I)-dppf complex catalyzes isomerizations of allyl propargyl ethers to allenic aldehydes in good yields from room temperature to 40°C. On the other hand, carbonyl migration reactions

Fused tetraeyclic heterocycles by thermally initiated intramolecular criss-cross cycloaddition of 3-substituted homoallenylaldazines

The thermally initiated intramolecular criss-cross cycloaddition of 3-substituted homoallenylaldazines 5 has been explored. Their cyclization led to interesting new fused heterocyclic systems 6 consisting of four five-membered rings with two nitrogen hete