29170-18-1Relevant academic research and scientific papers
Methoxycarbonylation of aliphatic diamines with dimethyl carbonate promoted by in situ generated hydroxide ion: A mechanistic consideration
Kim, Dae Won,Huh, Eun Soo,Park, Sang Do,Nguyen, Ly Vinh,Nguyen, Mai Dao,Kim, Hoon Sik,Cheong, Minserk,Nguyena, Dinh Quan
, p. 440 - 446 (2010)
The methoxycarbonylation reactions of aliphatic diamines with dimethyl carbonate are accelerated greatly in the presence of water. Theoretical investigations on the mechanistic aspects of the methoxycarbonylation of 1,6-hexanediamine strongly suggest that the hydroxide ion, generated in situ from the interaction of 1,6-hexanediamine with water, is an active catalytic species and plays a pivotal role in the rate-determining hydrogen abstraction step from the amino group.
