29170-79-4Relevant academic research and scientific papers
Structure-activity relationships of radioiodinated diphenyl derivatives with different conjugated double bonds as ligands for α-synuclein aggregates
Ono, Masahiro,Doi, Yuki,Watanabe, Hiroyuki,Ihara, Masafumi,Ozaki, Akihiko,Saji, Hideo
, p. 44305 - 44312 (2016)
It is generally recognized that aggregates of α-synuclein (α-syn) in the brain are closely associated with the pathogenesis of Parkinson's disease (PD). Therefore, the development of in vivo imaging probes targeting α-syn aggregates is currently expected.
Characterization of the Fluorescence Properties of 4-Dialkylaminochalcones and Investigation of the Cytotoxic Mechanism of Chalcones
Zhou, Bo,Jiang, Peixin,Lu, Junxuan,Xing, Chengguo
, p. 539 - 552 (2016/08/26)
Understanding the mechanisms responsible for the various biological activities of chalcones, particularly the direct cellular targets, presents an unmet challenge. Here, we prepared a series of fluorescent chalcone derivatives as chemical probes for their
Design, synthesis and evaluation of chalcone derivatives as anti- Inflammatory, antioxidant and antiulcer agents
Choudhary, Alka N.,Kumar, Arun,Juyal, Vijay
experimental part, p. 479 - 488 (2012/08/08)
In the present study, a series of chalcone derivatives were designed based on QSAR analysis. The designed compounds were synthesized by Claisen Schmidt condensation and evaluated for anti-inflammatory, antioxidant and antiulcer activities. The results of
