29171-72-0 Usage
Description
4-[(DIPROPYLAMINO)SULFONYL]BENZENE-1-CARBONYL CHLORIDE is a chemical compound characterized by a benzene ring with a carbonyl chloride group at the 1 position. It features a dipropylamino and a sulfonyl group attached to the benzene ring, making it a versatile building block in organic chemistry.
Uses
Used in Pharmaceutical Industry:
4-[(DIPROPYLAMINO)SULFONYL]BENZENE-1-CARBONYL CHLORIDE is used as an intermediate in the synthesis of various pharmaceuticals for its ability to introduce the carbonyl chloride group into other molecules, facilitating the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 4-[(DIPROPYLAMINO)SULFONYL]BENZENE-1-CARBONYL CHLORIDE serves as an intermediate in the production of agrochemicals, contributing to the synthesis of compounds that enhance crop protection and yield.
Used in Organic Chemistry Research:
4-[(DIPROPYLAMINO)SULFONYL]BENZENE-1-CARBONYL CHLORIDE is utilized as a reagent in organic chemistry reactions, enabling the introduction of the carbonyl chloride group into target molecules for the exploration of new chemical reactions and the synthesis of novel organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 29171-72-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,1,7 and 1 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 29171-72:
(7*2)+(6*9)+(5*1)+(4*7)+(3*1)+(2*7)+(1*2)=120
120 % 10 = 0
So 29171-72-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H18ClNO3S/c1-3-9-15(10-4-2)19(17,18)12-7-5-11(6-8-12)13(14)16/h5-8H,3-4,9-10H2,1-2H3
29171-72-0Relevant articles and documents
Discovery of novel bacterial RNA polymerase inhibitors: Pharmacophore-based virtual screening and hit optimization
Hinsberger, Stefan,Hüsecken, Kristina,Groh, Matthias,Negri, Matthias,Haupenthal, J?rg,Hartmann, Rolf W.
, p. 8332 - 8338 (2013/12/04)
The bacterial RNA polymerase (RNAP) is a validated target for broad spectrum antibiotics. However, the efficiency of drugs is reduced by resistance. To discover novel RNAP inhibitors, a pharmacophore based on the alignment of described inhibitors was used for virtual screening. In an optimization process of hit compounds, novel derivatives with improved in vitro potency were discovered. Investigations concerning the molecular mechanism of RNAP inhibition reveal that they prevent the protein-protein interaction (PPI) between σ70 and the RNAP core enzyme. Besides of reducing RNA formation, the inhibitors were shown to interfere with bacterial lipid biosynthesis. The compounds were active against Gram-positive pathogens and revealed significantly lower resistance frequencies compared to clinically used rifampicin.
Probenecidoxymethyl and 1-ethyl esters of ampicillin
-
, (2008/06/13)
New ampicillin derivatives, probenecidoxymethyl and 1-ethyl esters of ampicillin and their pharmaceutically acceptable salts, useful as antibiotics. A method for preparing these antibiotics by condensing probenecidoxymethyl or 1-ethyl halide with an acid
