291759-34-7

Upstream product

• 186301-25-7 4-N-phenylamino-5-iodo-7-(5-deoxy-2,3-O-isopropylidene-β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine 
• 98-80-6 phenylboronic acid 
• 123148-78-7 4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine 
• 186394-15-0 4-chloro-5-iodo-7-(5-deoxy-2,3-O-isopropylidene-β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine 
• 291535-34-7 5-deoxy-2,3-O-isopropylidene-α-D-ribofuranosyl chloride 
• 158112-53-9 (3aR,6R,6aR)-2,2,6-trimethyltetrahydro-2H-furo(3,4-d)(1,3)dioxol-4-ol 
• 186300-70-9 2-ethoxymethyleneimino-4-phenylpyrrole-3-carbonitrile 
• 54153-51-4 2-amino-3-cyano-4-phenylpyrrole 
• 186393-51-1 4-N-phenylamino-5-phenylpyrrolo[2,3-d]pyrimidine 

Downstream Products

• 144928-17-6 GP683 

Relevant academic research and scientific papers

Adenosine kinase inhibitors. 2. Synthesis, enzyme inhibition, and antiseizure activity of diaryltubercidin analogues

In the preceding article (Ugarkar et al. J. Med. Chem. 2000, 43) we reported that analogues of tubercidin are potent adenosine kinase (AK) inhibitors with antiseizure activity in the rat maximum electroshock (MES) model. Despite the discovery of several h

Design, synthesis and anticonvulsant activity of the potent adenosine kinase inhibitor GP3269

The pyrrolopyrimidine nucleoside GP3269 (12) was shown to be a potent and selective inhibitor of human adenosine kinase (IC50 = 11 nM) and to exhibit anticonvulsant activity in rats after oral administration. Synthesis of GP3269 was accomplishe