54153-51-4

Upstream product

• 5468-37-1 2-aminoacetophenone hydrochloride 
• 42003-88-3 ethyl 2-cyanoacetimidate 
• 613-89-8 2-Aminoacetophenone 
• 25384-14-9 2-aminoacetophenone hydrochloride 
• 109-77-3 malononitrile 
• 1074-82-4 potassium phtalimide 
• 532-27-4 1-chloroacetophenone 
• 71-43-2 benzene 
• 98-86-2 acetophenone 
• 1032-67-3 N-benzoylmethylphthalimide 
• 70-11-1 α-bromoacetophenone 
• 1816-88-2 2-azido-1-phenylethan-1-one 
• 1846-33-9 N-phenacylacetamide 

Downstream Products

• 114954-09-5 3-acetyl-4-methyl-7-phenylpyrrolo<1,2-a>pyrimidin-8-carbonitrile 
• 114954-07-3 ethyl 8-cyano-4,7-diphenylpyrrolo<1,2-a>pyrimidin-3-carboxylate 
• 112564-87-1 methyl 3-(3-cyano-4-phenyl-2-pyrrolylamino)-2-oxobutenoate 
• 116001-47-9 1,4-dihydro-4-oxo-7-phenylpyrrolo<1,2-a>pyrimidin-8-carbonitrile 
• 112564-83-7 ethyl 3-(3-cyano-4-phenyl-2-pyrrolylamino)-2-acetylpropenoate 
• 112564-84-8 ethyl 8-cyano-4-methyl-7-phenylpyrrolo<1,2-a>pyrimidin-3-carboxylate 
• 111074-46-5 ethyl 1,4-dihydro-8-cyano-4-oxo-7-phenylpyrrolo<1,2-a>pyrimidin-3-carboxylate 
• 111074-44-3 diethyl 2-<<(3-cyano-4-phenylpyrrol-2-yl)amino>methylen>propandioate 
• 114954-08-4 diethyl 8-cyano-7-phenylpyrrolo<1,2-a>pyrimidin-3,4-dicarboxylate 
• 291759-32-5 2-ethoxymethylmethyleneimino-4-phenylpyrrole-3-carbonitrile 
• 186300-70-9 2-ethoxymethyleneimino-4-phenylpyrrole-3-carbonitrile 
• 304678-61-3 ethyl 1-(3-cyano-4-phenylpyrrol-2-yl)-2-methyl-5-(3-nitrophenyl)pyrrole-3-carboxylate 
• 54760-24-6 2-amino-4-phenyl-1H-pyrrole-3-carboxylic acid amide 
• 304678-66-8 ethyl 5-(3-aminophenyl)-1-(3-cyano-4-phenylpyrrol-2-yl)-2-methylpyrrole-3-carboxylate 

Relevant academic research and scientific papers

MAP4K4 INHIBITORS

This invention relates to compounds that may be useful as inhibitors of Mitogen-activated Protein Kinase Kinase Kinase Kinase-4 (MAP4K4). The invention also relates to the use of these compounds, for example in a method of treatmentof cardiac conditions.In particular, the present invention relates to compounds of formula (I):

MAP4K4 INHIBITORS

This invention relates to pyrrolopyrimidine comprising compounds that may be useful as inhibitors of Mitogen-activated Protein Kinase Kinase Kinase Kinase-4 (MAP4K4). The invention also relates to the use of these pyrrolopyrimidine comprising compounds, f

dipyrromethene-type compound, colorant compositions comprising the same, quencher for improving of contrast ratio comprising the same and color filter comprising the same

The present invention relates to a dipyrromethene-type compound. Specifically, the present invention relates to the dipyrromethene-type compound which is a dipyrromethene metal complex represented by chemical formula 1 or chemical formula 2, and dipyrrome

Facile methods for the synthesis of 5-aryl and 5-iodo pyrrolo[2,3-d] pyrimidines

An efficient and environmentally benign one-pot method has been developed for the synthesis of 4-amino-5-arylpyrrolo[2,3-d]pyrimidines. Phthalimido acetophenones were reacted with cyanoacetamide to give 2-amino-4-phenyl-1H- pyrrole-3-carboxamides, which were further converted to 5-aryl-3H-pyrrolo[2,3-d] pyrimidin-4-ones. A novel method is also developed for the synthesis of 4-amino-5-iodopyrrolo[2,3-d]pyrimidines.

COMPOUND OR ITS TAUTOMER, METAL COMPLEX COMPOUND, COLORED PHOTOSENSITIVE CURING COMPOSITION, COLOR FILTER, AND PRODUCTION

Provided is a colored photosensitive curing composition useful for color filters in primary colors, including blue, green, and red, having a high molar absorption coefficient and allowing a reduction in film thickness and superior color purity and fastness. A colored photosensitive curing composition, comprising, as its colorant, a dipyrromethene-based metal complex compound obtained from a metal or metal compound and a dipyrromethene-based compound represented by the following Formula (I): wherein in Formula (I), R1 to R6 each independently represent a hydrogen atom or a substituent group; and R7 represents a hydrogen or halogen atom, or an alkyl, aryl or heterocyclic group.

Guanidine compound and heat sensitive recording material

An object of the present invention is to provide a heat sensitive recording material which can develop color at high density by the inclusion of a novel guanidine compound which is strongly basic and superior in diffusion resistance. The present invention for attaining the above-described object is a heat sensitive recording material comprising a substrate supporting thereon a heat sensitive recording layer containing a diazonium salt compound, a coupler which reacts with the diazonium salt compound when heated to develop color, and abase, wherein the heat sensitive recording layer includes as the base at least one of the guanidine compounds represented by the general formula (1): wherein, in the general formula (1), R1and R2represent an alkyl group or aryl group and may be the same or different, R3and R4represent a hydrogen atom, alkyl group or halogen atom and may be the same or different, and X represents a divalent connecting group.

7-alkyl- and 7-cycloalkyl-5-aryl-pyrrolo[2,3-d]pyrimidines - Potent inhibitors of the tyrosine kinase c-Src

7-Substituted-5-aryl-pyrrolo[2,3-d]pyrimidines have been prepared starting from α-bromoacetophenones. These compounds represent a novel class of potent inhibitors of the tyrosine kinase pp60c-Src with good specificity towards other tyrosine kinases (EGF-R, v-Abl).