2919-05-3

Usage

InChI:InChI=1/C5H6O/c1-2-3-4-5-6/h2,6H,1,5H2

Upstream product

• 689-97-4 3-buten-1-yne 
• 50-00-0 formaldehyd 
• 60-29-7 diethyl ether 
• 764-41-0 1,4-dichloro-2-butene 
• 14763-72-5 3-buten-1-ynylmagnesium bromide 
• 23418-85-1 3-butyn-1-yl p-toluenesulfonate 
• 593-60-2 Vinyl bromide 
• 107-19-7 propargyl alcohol 
• 74-86-2 acetylene 
• 92799-65-0 (3-chloro-5-hydroxy-pent-2-enyl)-trimethyl-ammonium; iodide 

Downstream Products

• 29943-42-8 Tetrahydro-4H-pyran-4-one 
• 4949-20-6 (E)-2,4-pentadien-1-ol 
• 101737-02-4 terephthalic acid di-pent-4-en-2-ynyl ester 
• 71313-47-8 2-pentyn-4-en-1-yl tosylate 
• 88830-57-3 5-p-tolylsulfonyl-2-bromo-2,3-pentadien-1-ol 
• 88830-58-4 5-p-tolylsulfonyl-4-bromo-2-pentyn-1-ol 
• 87832-30-2 (Z)-1-(3,5-Dinitrobenzoyloxy)penta-2,4-diene 
• 87832-31-3 (Z)-1-hydroxypenta-2,4-diene 
• 2060-59-5 tridec-1-ene-3,5,7,9,11-pentayne 
• 1890-28-4 divinylketone 
• 100138-47-4 tetrahydro-pyran-4-one-(4-phenyl semicarbazone) 

Relevant academic research and scientific papers

Stereoselective Synthesis of Pyrans from Epoxyalkenes: Dual Catalysis with Palladium and Br?nsted Acid

We describe regio- and stereoselective cycloisomerizations of alcohols tethered to epoxyalkenes, to construct alkene-substituted pyrans. These transformations are best catalyzed by Pd(PPh3)4 in the presence of phosphite ligands, and with diphenylphosphinic acid as an essential Br?nsted acid cocatalyst for activation of the epoxyalkene.

Selective indium-mediated 1,2,4-pentatrien-3-ylation of carbonyl compounds for the efficient synthesis of vinyl allenols

(Chemical Equation Presented) A highly selective synthetic method of functionalized vinyl allenols was developed from the reactions of various carbonyl compounds with organoindium reagent in situ generated from indium and 1-bromopent-4-en-2-yne derivatives. Treatment of vinyl allenols with gold catalyst, dienophile, or indium trihalide produced the functionalized dihydrofuran, cyclohexene, or 2-halo-1,3-diene derivatives in good to excellent yields.

Regiocontrol of the palladium-catalyzed tin hydride addition to Z-enynols: Remarkable Z-directing effects

(Figure Presented) Palladium-catalyzed hydrostannation of substituted Z- and E-enynols is discussed and compared. The regioselectivity of the H-Sn bond addition was found to be controlled by the geometry of the double bond (Z- or syn-directing effect) rather than the nature of its substituents, Exclusively α-vinyl stannanes were obtained from Z-enynols having various substituents on the double bond regardless of their electronic, steric, or chelating natures.

Development of a method for the synthesis of α-substituted α,β- unsaturated lactones based on stille-type Pd-catalyzed carbonylation of (Z)- ω-iodoalkenols. An efficient and selective synthesis of (+)-hamabiwalactone B

Pd-Catalyzed carbonylative lactonization of (Z)-ω-iodoalkenols can be applied to synthesize α/β-unsaturated lactones containing an alkenyl or alkynyl substituent in the α position, providing a generally superior alternative to recently developed methods involving Pd-catalyzed α- substitution of α-stannyl esters, as exemplified by a highly expeditious synthesis of (+)-hamabiwalactone B.

Dihydropyridazinones, pyridazinones and related compounds as fungicides

This invention relates to substituted dihydropyridazinones, pyridazinones and related compounds, of the formula STR1 wherein A, Q, D and R1 are as defined within, compositions containing these compounds and methods of controlling agricultural and mammalian fungal diseases.

Eneynols from acetylenes and propargylic alcohols

Eneynols are prepared from terminal acetylenes and propargylic alcohols using a Cu+, Ag+ and/or Au+ halide catalyst.