29207-90-7

Upstream product

• 25835-12-5 morpholine-4-carboxylic acid (4-bromo-benzylidene)-hydrazide 
• 29207-88-3 N'-[(4-bromo-phenyl)-chloro-methylene]-morpholine-4-carbohydrazonoyl chloride 
• 5765-65-1 4-(benzoyloxy)morpholine 
• 41420-90-0 2-(4-bromophenyl)-1,3,4-oxadiazole 
• 29207-87-2 4-bromo-N'-dichloromethylene-benzohydrazonoyl chloride 

Relevant academic research and scientific papers

Copper-catalyzed electrophilic amination of heteroarenes and arenes by C-H zincation

Direct amination of heteroarenes and arenes has been achieved in a one-pot C-H zincation/copper-catalyzed electrophilic amination procedure. This amination method provides an efficient and rapid approach to access a diverse range of heteroaromatic and aromatic amines including those previously inaccessible using C-H amination methods. The mild reaction conditions and good functional-group compatibility demonstrate its great potential for the synthesis of important and complex amines. Direct amination of heteroarenes and arenes has been achieved in a one-pot zincation/Cu(OAc)2-catalyzed amination sequence using O-acylhydroxylamines. The method provides a rapid and efficient approach to a range of aromatic and heteroaromatic amines, including those which were previously inaccessible by using C-H amination methods. tmp=2,2,6,6- tetramethylpiperidide.