2923-61-7Relevant academic research and scientific papers
Preparation method of 2-(5-fluorine-2,4-binitro phenoxy) acetic acid
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Paragraph 0036-0047, (2019/10/01)
The invention discloses a preparation method of 2-(5-fluorine-2,4-binitro phenoxy) acetic acid. The preparation method comprises the following steps that 1,5-fluorine-2,4-dinitrobenzene and ethylene glycol are used as raw materials; under the effect of al
Phenoxiacetic ester process and intermediates for the synthesis of
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Paragraph 0181; 0182, (2016/10/10)
The invention discloses a synthetic method of phenoxy acetate and an intermediate thereof. The method is as below: first reacting glycolic acid with organic amine to generate salt; then conducting nucleophilic substitution reaction with the product with aryl halides; and finally conducting esterification reaction to obtain the phenoxyl acetate compound (I). The method not only overcomes the shortcomings in the prior art for preparation of phenoxyl acetate intermediate, but also uses cheap and easily available raw materials, while largely inhibiting generation of hydrolysis byproduct nitrophenol in the aromatic nucleophilic substitution reaction, so as to improve the reaction yield, reduce the wastes, and benefit industrial production.
