29232-39-1

Usage

Uses

Used in Organic Synthesis:
2,3-Dibromo-5-methylpyridine is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for a range of chemical reactions, making it a valuable building block for the creation of new molecules with potential applications in pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Material Science:
In the field of material science, 2,3-dibromo-5-methylpyridine is employed as a component in the development of new materials with specific properties. Its incorporation into polymers, for instance, can lead to materials with altered electronic, optical, or mechanical characteristics, depending on the desired application. This can be particularly useful in the design of advanced materials for electronics, sensors, or other high-tech applications.

InChI:InChI=1/C6H5Br2N/c1-4-2-5(7)6(8)9-3-4/h2-3H,1H3

Upstream product

• 78-85-3 2-methylpropenal 
• 3252-43-5 dibromoacetonitrile 
• 17282-00-7 3-bromo-5-methylpyridin-2-amine 

Downstream Products

• 1259313-80-8 benzyl 4-(3-bromo-5-methylpyridin-2-yl)piperazine-1-carboxylate 
• 1187386-02-2 tert-butyl 4-(3-bromo-5-methylpyridin-2-yl)piperazine-1-carboxylate 

Relevant academic research and scientific papers

ALPHA-CARBOLINE DERIVATIVES AND METHODS FOR PREPARATION THEREOF

To provide methods for preparing alpha-carboline derivatives in few steps, as well as conveniently and industrially advantageously. A method for preparation of a compound represented by Formula (II) or a salt thereof, comprising subjecting a compound represented by Formula (I) or a salt thereof to a ring closure reaction in the presence of a palladium catalyst, a ligand, and a base; a method for preparation of a compound represented by Formula (IX) or a salt thereof, comprising subjecting a compound represented by Formula (VII) or a salt thereof to a ring closure reaction in the presence of a palladium catalyst, a ligand, and a base, and subsequently to an aromatization reaction; and methods for preparation of compounds represented by Formulae (XV), (XVII), and (XIX) or a salt thereof, comprising subjecting respective compounds represented by Formulae (II) and (IX) or a salt thereof to a reaction for introducing a leaving group when necessary, and subsequently to a coupling reaction: wherein the symbols respectively represent the same meaning as defined in the present specification.

Synthesis of Halogenated Pyridines via the CuCl-Catalyzed Addition of Polyhaloacetonitriles to Olefins

Halogenated acetonitriles add smoothly to acrolein, methacrolein, and methacrolein dimethyl acetal in the presence of a catalytic amount of CuCl and triphenylphosphine, tri-n-butylphosphine, or triethylamine to give halogenated difunctional adducts.The adducts have been cyclized in high yields under acidic conditions to halogenated pyridines.