29246-36-4

Basic information

• Product Name: N-(4-chlorophenyl)undec-10-enamide
• CAS NO: 29246-36-4
• Molecular Formula: C₁₇H₂₄ClNO
• Molecular Weight: 293.8316
• Mol File: 29246-36-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 450.7°C at 760 mmHg
• Flash Point: 226.4°C
• Density: 1.056g/cm³
• Vapor Pressure: 2.58E-08mmHg at 25°C
• Refractive Index: 1.536
• CAS DataBase Reference: N-(4-chlorophenyl)undec-10-enamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-chlorophenyl)undec-10-enamide(29246-36-4)
• EPA Substance Registry System: N-(4-chlorophenyl)undec-10-enamide(29246-36-4)

Safety Data

• Hazardous Substances Data: 29246-36-4(Hazardous Substances Data)

Upstream product

• 38460-95-6 undec-10-enoyl chloride 
• 106-47-8 4-chloro-aniline 
• 112-38-9 10-undecenoic acid 
• 100-00-5 4-chlorobenzonitrile 

Downstream Products

• 76691-62-8 N-10-Undecenyl-N-p-chlorophenylamine 
• 76691-57-1 10-Bromoundecanyl-p-chloroanilide 

Relevant articles and documents

Direct Amidation of Carboxylic Acids with Nitroarenes

N-Aryl amides are an important class of compounds in pharmaceutical and agrochemical chemistry. Rapid and low-cost synthesis of N-aryl amides remains in high demand. Herein, we disclose an operationally simple process to access N-aryl amides directly from readily available nitroarenes and carboxylic acids as coupling substrates. This method involves the in situ activation of carboxylic acids to acyloxyphosphonium salt for one-pot amidation, without the need for isolation of the corresponding synthetic intermediates. Furthermore, the ease of preparation and workup allow the quick and efficient synthesis of a wide range of N-aryl amides, including several amide-based druglike and agrochemical molecules.