29246-94-4Relevant academic research and scientific papers
Asymmetric organozincate additions to ethyl 2,2,2-trifluoropyruvate
Gosselin, Francis,Britton, Robert A.,Mowat, Jeffrey,O'Shea, Paul D.,Davies, Ian W.
, p. 2193 - 2196 (2007)
A chromatography-free synthesis of enantiomerically enriched chiral α-trifluoromethyl α-hydroxy acids prepared via an asymmetric (R)-BINOL-mediated organozincate addition to ethyl 2,2,2-trifluoropyruvate (1) is reported. Georg Thieme Verlag Stuttgart.
An efficient method for the preparation of Chiral Mosher's acid analogues
Kawano, Yoshikazu,Kaneko, Nobuya,Mukaiyama, Teruaki
, p. 304 - 305 (2007/10/03)
A diastereoselective trifluoromethylation of chiral α-keto esters derived from isosorbide with TMSCF3 in the presence of a Lewis-base catalyst gave the corresponding trifluoromethylated α-hydroxy esters in good yields with moderate to high dias
