292624-77-2Relevant academic research and scientific papers
Tritylisation of pyrene, perylene and coronene: A new family of switchable fluorescent labels
Shchepinov, Mikhail S.,Korshun, Vladimir A.,Egeland, Ryan D.,Southern, Edwin M.
, p. 4943 - 4948 (2007/10/03)
The synthesis of novel fluorescent labels based on pyrene, perylene and coronene is described. Due to the trityl-type structure, their fluorescence may be reversibly switched on and off by changing the pH. This property can be used to expand the palette of fluorophores available for multicolour DNA detection on DNA chips. Some FRET and surface chemistry applications are also demonstrated. (C) 2000 Elsevier Science Ltd.
