292820-05-4Relevant articles and documents
Quinone - Annonaceous acetogenins: Synthesis and complex I inhibition studies of a new class of natural product hybrids
Arndt, Sabine,Emde, Ulrich,Baeurle, Stefan,Friedrich, Thorsten,Grubert, Lutz,Koert, Ulrich
, p. 993 - 1005 (2001)
The natural product hybrids quinone-mucocin and quinone- squamocin D were synthesized. In these hybrids, the butenolide unit of the annonaceous acetogenins mucocin and squamocin D is exchanged for the quinone moiety of the natural complex I substrate ubiq
Natural-product hybrids: Design, synthesis, and biological evaluation of quinone - Annonaceous acetogenins
Hoppen, Sabine,Emde, Ulrich,Friedrich, Thorsten,Grubert, Lutz,Koert, Ulrich
, p. 2099 - 2102 (2007/10/03)
Replacement of the butyrolactone unit of the natural products with a quinone subunit has resulted in the synthesis of natural-product hybrids of quinone-mucocin (1). These compounds, which are combined from partial structures of annonaceous acetogenins an