292855-70-0Relevant academic research and scientific papers
Application of design of experiments (Doe) approach for the optimization of phase-transfer catalyzed biginelli dihydropyrimidinone (dhpm) synthesis
Durai Ananda Kumar, T.,Satyanarayana, K.,Subrahmanyam, C. V. S.,Swathi, N.
, p. 520 - 531 (2021/07/25)
The conventional Biginelli synthesis is more cumbersome and produces lower yields. Several improved methods are reported in the literature to replace the Biginelli catalyst. The design of biocompatible organic transformation is a major concern and a versa
Synthesis of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) by natural L-ascorbic acid
Kodape, Manisha M.,Gawhale, Nandkishor D.,Awjare, Nikita V.
, p. 671 - 675 (2015/05/27)
Extremely facile, environmental friendly and solvent free method for the synthesis of dihydropyrimidones (DHPMs) by naturally occurring L-Ascorbic acid (Lemon Juice-three drops) in microwave at 120°C has been described. The present methodology includes in
New magnetic nanocomposites of ZrO2-Al2O 3-Fe3O4 as green solid acid catalysts in organic reactions
Wang, Anqi,Liu, Xiang,Su, Zhongxing,Jing, Huanwang
, p. 71 - 80 (2014/01/06)
A series of magnetic solid acid nano-catalysts were designed and prepared through a facile co-precipitate approach. The original nanocomposites ZrO 2-Al2O3-Fe3O4 were characterized by means of ICP-AES
Bronsted acidic ionic liquids of aza-crown ether complex cations: Preparation and applications in organic reactions
Cheng, Chen,Jing, Huanwang
, p. 34325 - 34331 (2014/11/07)
A series of novel Bronsted acidic ionic liquids composed of an aza-crown ether chelated potassium cation and various anions, were designed, synthesized and characterised by FTIR, NMR and mass spectrometry, thermogravimetric differential thermal analysis (TG-DTA) and elemental analysis. These new Bronsted acidic ionic liquids of aza-crown ether complex cations (aCBAILs) were applied as catalysts to the Biginelli reaction, Mannich reaction and synthesis of bis-(4-hydroxycoumarin-3-yl)methanes. These organic reactions were achieved in good yields under mild reaction conditions. Moreover, these new IL catalysts can be recycled several times. This journal is the Partner Organisations 2014.
A facile approach for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones using a microwave promoted Biginelli protocol in ionic liquid
Dadhania, Abhishek N.,Patel, Vaibhav K.,Raval, Dipak K.
, p. 921 - 926,6 (2020/09/09)
Carboxy functionalized ionic liquid [cmmim][BF4] has been demonstrated to be an efficient and green catalyst for the one pot synthesis of 3,4-dihydropyrimidin-2-(1H)-ones heterocycles under microwave irradiation. The ionic liquid-microwave stra
Facile aromatization of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) by iodine
Kodape, Manisha M.,Aswar, Anand S.,Gawhale, Nandkishor D.,Humne, Vivek T.,Mir, Bilal Ahmad
, p. 1339 - 1342 (2013/02/22)
A facile aromatization of 3,4-dihydropyrimidin-2(1H)-ones using iodine in dimethyl sulfoxide under microwave irradiation was carried out which is more efficient and gives high yield in less time; presently it is the most important catalyst for dehydrogena
An efficient one-pot synthesis of dihydropyrimidinones catalyzed by zirconium hydrogen phosphate under solvent-free conditions
Besoluk, Senol,Kucukislamoglu, Mustafa,Zengin, Mustafa,Arslan, Mustafa,Nebioglu, Mehmet
experimental part, p. 411 - 416 (2010/11/03)
A simple, efficient, and practical procedure for the Biginelli reaction using zirconium hydrogen phosphate [Zr(H2 PO4) 2] as a novel solid acid catalyst is described under solvent-free conditions in high yields. The cataly
Three component reaction: An efficient synthesis of 3,4-dihydropyrimidin-2(1H)-ones and thiones using heterogeneous catalyst
Kamble, Vinod Tribhuvannathji,Muley, Dnyanoba Baburao,Atkore, Sandeep Tukaram,Dakore, Sharad Digambarrao
experimental part, p. 388 - 392 (2010/10/02)
Fluoroboric acid supported on silica gel (HBF4-SiO2) catalyzes efficiently the three component condensation of an aldehyde, a 1,3-dicarbonyl compound and urea or thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones an
Sodium tetrafluoroborate as a new and highly efficient catalyst for one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones and thiones
Bandgar,Kamble,Bavikar,Dhavane, Abasaheb
, p. 263 - 266 (2008/02/10)
Sodium tetrafluoroborate (NaBF4) is found to catalyze the three component condensation of an aldehyde, 1,3-dicarbonyl compound and urea or thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones and thiones in high yields. This met
Investigation of the effects of some heat sinks in microwave-assisted synthesis of some biginelli compounds
Mobinikhaledi,Foroughifar,Fathinejad Jirandehi
, p. 2259 - 2263 (2007/10/03)
Pyrimidine derivatives 4a-e were synthesized by Biginelli reaction under microwave irradiation. The effectiveness of different baths or containers including ceramic, silica gel, potsherd, alumina, and molecular sieve as heat sinks in mediating the microwa
