293313-58-3

Basic information

• Product Name: Carbamic acid, [(4-methylphenyl)sulfonyl](1-methyl-2-propynyl)-, 1,1-dimethylethyl ester
• CAS NO: 293313-58-3
• Molecular Formula: C16H21NO4S
• Molecular Weight: 323.413
• Mol File: 293313-58-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(4-methylphenyl)sulfonyl](1-methyl-2-propynyl)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(4-methylphenyl)sulfonyl](1-methyl-2-propynyl)-, 1,1-dimethylethyl ester(293313-58-3)
• EPA Substance Registry System: Carbamic acid, [(4-methylphenyl)sulfonyl](1-methyl-2-propynyl)-, 1,1-dimethylethyl ester(293313-58-3)

Safety Data

• Hazardous Substances Data: 293313-58-3(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 70-55-3 toluene-4-sulfonamide 
• 18303-04-3 N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide 
• 2028-63-9 but-3-yn-2-ol 

Downstream Products

• 491879-61-9 4-methyl-N-(1-methylprop-2-ynyl)-benzenesulfonamide 
• 1289257-32-4 C₁₇H₁₉NO₃S 
• 293313-59-4 N-2-(Pent-3-ynyl)-4-methylbenzenesulfonamide 

Relevant articles and documents

Solid form of heteroaryl-fused tetrahydropyridine compound and preparation method of heteroaryl-fused tetrahydropyridine compound

The present application discloses a solid form of a heteroaryl-fused tetrahydropyridine compound of a formula (I) and a preparation method thereof. The solid form comprises a crystal A, a crystal B, acrystal C and an amorphous form, wherein the crystal B has good physicochemical stability.

Developing a diastereoselective intramolecular [4 + 3] cycloaddition of nitrogen-stabilized oxyallyl cations derived from N-sulfonyl-substituted allenamides

Efforts toward achieving a practical and diastereoselective intramolecular [4 + 3] cycloaddition of nitrogen-stabilized oxyallyl cations with tethered dienes are described. Epoxidation of N-sulfonyl substituted allenamides with dimethyldioxirane (DMDO) generates nitrogen-stabilized oxyallyl cations that readily undergo stereoselective [4 + 3] cycloaddition with dienes. Selectivity is found to depend on the tethering length as well as the stability of the oxyallyl cation intermediate, whether generated from N-carbamoyl- or N-sulfonyl-substituted allenamides. The use of chiral N-sulfonyl-substituted allenamides provided minimal diastereoselectivity in the cycloaddition, while high diastereoselectivity can be achieved with a stereocenter present on the tether. These studies provide further support for the synthetic utility of allenamides.