293322-40-4

Basic information

• Product Name: 3-Cloro-1-phenylpropyl butanoate
• Synonyms: 3-Cloro-1-phenylpropyl butanoate
• CAS NO: 293322-40-4
• Molecular Weight: 240.73
• Mol File: 293322-40-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Cloro-1-phenylpropyl butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cloro-1-phenylpropyl butanoate(293322-40-4)
• EPA Substance Registry System: 3-Cloro-1-phenylpropyl butanoate(293322-40-4)

Safety Data

• Hazardous Substances Data: 293322-40-4(Hazardous Substances Data)

Upstream product

• 106-31-0 butanoic acid anhydride 
• 18776-12-0 3-chloro-1-phenyl-propan-1-ol 
• 936-59-4 3-chloropropiophenone 

Downstream Products

• 112066-67-8 (R)-N-methyl-3-(2-methoxyphenoxy)-3-phenyl-1-propanamine 
• 114446-49-0 -(+)-1-chloro-3-phenyl-3-(2-methoxyphenoxy)propane 
• 114446-47-8 -(-)-1-chloro-3-phenyl-3-(2-methylphenoxy)propane 
• 114446-48-9 -(+)-1-chloro-3-phenyl-3-<4-(trifluoromethyl)phenoxy>propane 
• 54910-89-3 (R)-fluoxetine 
• 105314-52-1 (R)-tomoxetine 
• 100306-34-1 3-chloro-1-phenylpropanol 
• 100306-33-0 (1R)-3-chloro-1-phenylpropanol 

Relevant articles and documents

Chemoenzymatic synthesis of the non-tricyclic antidepressants Fluoxetine, Tomoxetine and Nisoxetine

3-Chloro-1-phenylpropan-1-ol and the corresponding butanoate, 3-chloro-1-phenyl-1-propyl butanoate, were kinetically resolved using lipase B from Candida antarctica catalysis by transesterification and hydrolysis respectively. The resulting chiral building blocks (S)- and (R)-3-chloro-1-phenylpropanol were converted into both enantiomers of the antidepressant drugs, Fluoxetine, Tomoxetine and Nisoxetine. The Royal Society of Chemistry 2000.