29334-17-6

Usage

Uses

Used in Pharmaceutical Industry:
(4-Bromophenyl)(4-Methylphenyl)Methanol is used as an intermediate in the synthesis of various pharmaceutical drugs. Its unique structure allows for the creation of a wide range of compounds with potential therapeutic applications.
Used in Chemical Reactions:
In the chemical industry, (4-Bromophenyl)(4-Methylphenyl)Methanol is used as a reagent in various chemical reactions. Its versatility and reactivity make it a valuable component in the development of new chemical compounds and materials.
Safety:
As with all chemicals, (4-Bromophenyl)(4-Methylphenyl)Methanol should be handled with care and in accordance with safety procedures to ensure the safety of both the individuals working with the compound and the environment.

Upstream product

• 106-38-7 para-bromotoluene 
• 1122-91-4 4-bromo-benzaldehyde 
• 5084-80-0 tri(4-tolyl)boroxine 
• 5720-05-8 4-methylphenylboronic acid 

Downstream Products

• 76693-57-7 (4-bromophenyl)(p-tolyl)methanone 
• 478678-66-9 C₃₅H₃₄N₂O₆ 
• 51310-29-3 methyl 4-(4-bromobenzoyl)benzoate 
• 51310-30-6 4-(4'-bromobenzoyl)benzoic acid 
• 18066-90-5 4-Methyl-4'-brom-diphenyl-brommethan 

Relevant academic research and scientific papers

Bio-inspired asymmetric aldehyde arylations catalyzed by rhodium-cyclodextrin self-inclusion complexes

Transition-metal catalysts are powerful tools for carbon-carbon bond-forming reactions that are difficult to achieve using native enzymes. Enzymes that exhibit inherent selectivities and reactivities through host-guest interactions have inspired widesprea

A nontransmetalation reaction pathway for anionic four-electron donor-based palladacycle-catalyzed addition reactions of arylborons with aldehydes

A nontransmetalation reaction pathway for anionic four-electron donor-based (Type I) palladacycle-catalyzed addition reactions of arylborons with aldehydes is described. This new reaction pathway offers new catalysis opportunities for Type I palladacycle-catalyzed addition reactions such as the exceptionally low catalyst loading catalysis, with the catalyst loading as low as 0.0005 mol %. This new pathway may be applicable for other transition metal-catalyzed addition reactions and might lead to the development of new reactions including sequential/tandem reactions.

A homogeneous, recyclable polymer support for rh(I)-catalyzed c-c bond formation

A robust and practical polymer-supported, homogeneous, recyclable biphephos rhodium(I) catalyst has been developed for C-C bond formation reactions. Control of polymer molecular weight allowed tuning of the polymer solubility such that the polymer-supported catalyst is soluble in nonpolar solvents and insoluble in polar solvents. Using the supported rhodium catalysts, addition of aryl and vinylboronic acids to the electrophiles such as enones, aldehydes, N-sulfonyl aldimines, and alkynes occurs smoothly to provide products in high yields. Additions of terminal alkynes to enones and industrially relevant hydroformylation reactions have also been successfully carried out. Studies show that the leaching of Rh from the polymer support is low and catalyst recycle can be achieved by simple precipitation and filtration.

Orthoplatinated triarylphosphite as a highly efficient catalyst for addition reactions of arylboronic acids with aldehydes: Low catalyst loading catalysis and a new tandem reaction sequence

(Chemical Equation Presented) Readily available, air/moisture-stable orthoplatinated triarylphosphite catalyzes the addition reactions of arylboronic acids with aldehydes with the catalyst loading as low as 0.01%. It also cataylzes a new tandem reaction of arylboronic acids with α,β- unsaturated aldehydes to form 1,3-diaryl-1-propanols. Our study provides a new paradigm for the application of orthoplatinated triarylphosphites, and may pave the road to develop other Pt(II) catalysts for such addition reactions and other tandem reactions with such addition reactions as part of the reaction sequence.

New photoactivators for multiphoton excited three-dimensional submicron cross-linking of proteins: Bovine serum albumin and type 1 collagen

We report the synthesis and optical characterization of two new photoactivators and demonstrate their use for multiphoton excited three-dimensional free-form fabrication with proteins. These reagents were developed with the goal of cross-linking Type 1 collagen. This cross-linking process produces structures on the micron and submicron size scales. A rose bengal diisopropyl amine derivative combines the classic photoactivator and co-initiator system into one molecule, reducing the reaction kinetics and increasing cross-linking efficiency. This derivative was successful at producing stable structures from collagen, whereas rose bengal alone was not effective. A benzophenone dimer connected by a flexible diamine tether was also synthesized. This activator has two photochemically reactive groups and is highly efficient in cross-linking bovine serum albumin and Type 1 collagen to form stable, robust structures. This approach is more flexible in terms of cross-linking a variety of proteins than by traditional benzophenone photochemistry. The photophysical properties vary greatly from that of benzophenone, with the appearance of a new, lower energy absorption band (λmax～370 nm in water) and broad, visible emission band (～500 nm maximum). This absorption band is highly solvatochromic, suggesting it arises, at least in part, from a charge transfer interaction. Collagens are typically difficult to cross-link photochemically, and the results here suggest that these two new activators will be suitable for cross-linking other forms of collagen and additional proteins for biomedical applications such as the de novo assembly of biomimetic tissue scaffolds.