2935-89-9Relevant academic research and scientific papers
Scale up of a ritter reaction
Chang, Sou-Jen
, p. 232 - 234 (1999)
The Ritler reaction of secondary or tertiary alcohols with acrylonitrile provides easy access to acrylamides which would otherwise be difficult to prepare. A safe procedure for conducting this reaction is described.
Process for preparing isothiazolones
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, (2008/06/13)
The process involves the cofeeding of an acrylonitrile with an appropriate alcohol or its equivalent and a strong acid to form an acrylamide which is thiolated to form a mercapto-propionamide which is halogenated to afford the desired biocidally active isothiazolones. This invention relates to a novel process for preparing N-substituted 3-mercaptopropionamides, an intermediate in the preparation of isothiazolones.
