293732-27-1Relevant academic research and scientific papers
An efficient entry to pyrrolo[1,2-b]isoquinolines and related systems through Parham cyclisation
Ruiz, Javier,Ardeo, Ainhoa,Ignacio, Roberto,Sotomayor, Nuria,Lete, Esther
, p. 3311 - 3324 (2005)
Aryllithiums generated by lithium-iodine exchange undergo intramolecular cyclisation to give pyrrolo[1,2-b]isoquinolines, in high yields. The best results were obtained when Weinreb or morpholine amides were used as internal electrophiles. The procedure h
Stereoretentive Intramolecular Glycosyl Cross-Coupling: Development, Scope, and Kinetic Isotope Effect Study
Yi, Duk,Zhu, Feng,Walczak, Maciej A.
supporting information, p. 4627 - 4631 (2018/08/07)
A series of cyclic C-glycosides were synthesized using the palladium-catalyzed stereoretentive intramolecular glycosylation of aryl iodides by employing a bulky phosphine ligand. A variety of functional groups are tolerated in the reaction, and enantioenr
Parham-type cycliacylation with Weinreb amides. Application to the synthesis of fused indolizinone systems
Ruiz, Javier,Sotomayor, Nuria,Lete, Esther
, p. 1115 - 1117 (2007/10/03)
(Matrix presented) Weinreb amides behave as efficient internal electrophiles in Parham-type cycliacylation reactions. Thus, aryl- and heteroaryllithiums generated by lithium-halogen exchange undergo intramolecular cyclization to give fused indolizinone systems as pyrrolo[1,2-b]isoquinolines, thieno[2,3-f]indolizinones, and pyrrolo[1,2-b]acridinones in high yields.
