524024-81-5

Basic information

• Product Name: 1H-Pyrrole-2-carboxamide, 1-[(2-iodo-4,5-dimethylphenyl)methyl]-N-methoxy-N-methyl-
• CAS NO: 524024-81-5
• Molecular Formula: C16H19IN2O2
• Molecular Weight: 398.244
• Mol File: 524024-81-5.mol

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-2-carboxamide, 1-[(2-iodo-4,5-dimethylphenyl)methyl]-N-methoxy-N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-2-carboxamide, 1-[(2-iodo-4,5-dimethylphenyl)methyl]-N-methoxy-N-methyl-(524024-81-5)
• EPA Substance Registry System: 1H-Pyrrole-2-carboxamide, 1-[(2-iodo-4,5-dimethylphenyl)methyl]-N-methoxy-N-methyl-(524024-81-5)

Safety Data

• Hazardous Substances Data: 524024-81-5(Hazardous Substances Data)

Upstream product

• 634-97-9 pyrrole-2-carboxyl acid 
• 851384-78-6 (2-iodo-4,5-dimethylphenyl)methanol 
• 293732-27-1 1-(bromomethyl)-2-iodo-4,5-dimethylbenzene 
• 368211-06-7 1H-pyrrole-2-carboxylic acid methoxymethylamide 

Relevant articles and documents

An efficient entry to pyrrolo[1,2-b]isoquinolines and related systems through Parham cyclisation

Aryllithiums generated by lithium-iodine exchange undergo intramolecular cyclisation to give pyrrolo[1,2-b]isoquinolines, in high yields. The best results were obtained when Weinreb or morpholine amides were used as internal electrophiles. The procedure h

Parham-type cycliacylation with Weinreb amides. Application to the synthesis of fused indolizinone systems

(Matrix presented) Weinreb amides behave as efficient internal electrophiles in Parham-type cycliacylation reactions. Thus, aryl- and heteroaryllithiums generated by lithium-halogen exchange undergo intramolecular cyclization to give fused indolizinone systems as pyrrolo[1,2-b]isoquinolines, thieno[2,3-f]indolizinones, and pyrrolo[1,2-b]acridinones in high yields.