293732-35-1Relevant academic research and scientific papers
Metalation-cyclisation sequence on N-(o-halobenzyl)pyrroles. Synthesis of pyrrolo[1,2-b]isoquinolones
Ardeo, Ainhoa,Lete, Esther,Sotomayor, Nuria
, p. 5211 - 5214 (2000)
Parham-type cyclisation of N-(o-halobenzyl)pyrroles has been investigated. Aryllithiums generated from metalation of N-(o- iodobenzyl)pyrroles undergo intramolecular cyclisation to give pyrrolo[1,2- b]isoquinolinones in moderate to good yields, if the N,N
An efficient entry to pyrrolo[1,2-b]isoquinolines and related systems through Parham cyclisation
Ruiz, Javier,Ardeo, Ainhoa,Ignacio, Roberto,Sotomayor, Nuria,Lete, Esther
, p. 3311 - 3324 (2007/10/03)
Aryllithiums generated by lithium-iodine exchange undergo intramolecular cyclisation to give pyrrolo[1,2-b]isoquinolines, in high yields. The best results were obtained when Weinreb or morpholine amides were used as internal electrophiles. The procedure h
