293742-82-2

Usage

Uses

Used in Pharmaceutical Industry:
(R)-methyl 2-amino-3-(4-tolyl)propanoate hydrochloride is used as a pharmaceutical intermediate for the synthesis of various drugs. Its role in drug development is crucial due to its ability to serve as a building block for creating new medications with potential applications in treating neurological disorders, psychiatric disorders, and chronic pain.
Additionally, as the compound's precise mechanisms of action and specific therapeutic uses are still under investigation, it holds promise as a valuable tool in the advancement of pharmaceutical research and the creation of innovative treatment options for patients suffering from a variety of health issues.

Upstream product

• 67-56-1 methanol 
• 196107-03-6 (R)-methyl 2-amino-3-(4-tolyl)propanoate 
• 1323413-13-3 (R)-methyl 2-azido-3-(4-cyanophenyl)propanoate 
• 1323413-05-3 (S)-methyl 2-chloro-3-(4-cyanophenyl)propanoate 
• 1323412-94-7 (S)-2-chloro-3-(4-cyanophenyl)propanoic acid 
• 1323412-89-0 (Z)-2-chloro-3-(4-cyanophenyl)acrylic acid methyl ester 

Downstream Products

• 1610691-85-4 (R)-N-[N-(2,2-dimethoxyethyl)glycinyl]-4-methylphenylalanine methyl ester 
• 1610691-81-0 (R)-N-(2-chloroacetyl)-4-methylphenylalanine methyl ester 

Relevant academic research and scientific papers

A diastereoselective construction of pyrazinoisoquinoline skeletons via tandem cyclization of phenylalanine derivatives: A facile synthesis of optically active pyrazinoisoquinolines

A facile and stereocontrolled construction of optically active pyrazinoisoquinoline skeletons based on tandem cyclization of enantiopure phenylalanine derivatives was examined. The reaction provided optically active 6,11b-trans pyrazinoisoquinoline ring systems in excellent diastereoselectivity, and this method was applicable to the cyclization of phenylalanine derivatives with diverse substituents.

Biocatalyzed enantioselective reduction of activated C=C bonds: Synthesis of enantiomerically enriched α-halo-β-arylpropionic acids

The enantioselective biocatalyzed reduction of the C=C bond of some (Z)-methyl α-halo-β-arylacrylates was investigated. The reaction was performed by baker's yeast fermentation and Old Yellow Enzymes 1-3 mediated biotransformations. The final products wer