293758-67-5

Basic information

• Product Name: 5-Nitro-3-phenyl-1H-indazole
• Synonyms: 5-Nitro-3-phenyl-1H-indazole
• CAS NO: 293758-67-5
• Molecular Formula: C₁₃H₉N₃O₂
• Molecular Weight: 239.22946
• Mol File: 293758-67-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 491.8 °C at 760 mmHg
• Flash Point: 251.2 °C
• Appearance: /
• Density: 1.389 g/cm³
• Vapor Pressure: 2.44E-09mmHg at 25°C
• Refractive Index: 1.716
• CAS DataBase Reference: 5-Nitro-3-phenyl-1H-indazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Nitro-3-phenyl-1H-indazole(293758-67-5)
• EPA Substance Registry System: 5-Nitro-3-phenyl-1H-indazole(293758-67-5)

Safety Data

• Hazardous Substances Data: 293758-67-5(Hazardous Substances Data)

Usage

General Description

5-Nitro-3-phenyl-1H-indazole is a chemical compound with the molecular formula C13H9N3O2. It is an indazole derivative, which is a class of heterocyclic aromatic compounds. The compound contains a nitro group and a phenyl group attached to the indazole ring structure. It is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. The compound has been studied for its potential biological activities, including its antimicrobial and antitumor properties. Additionally, it may have potential applications in the field of materials science and organic electronics due to its unique chemical and electronic properties.

InChI:InChI=1/C13H9N3O2/c17-16(18)10-6-7-12-11(8-10)13(15-14-12)9-4-2-1-3-5-9/h1-8H,(H,14,15)

Upstream product

• 5401-94-5 5-nitroindazole 
• 100-25-4 para-dinitrobenzene 
• 1666-17-7 benzaldehyde p-toluenesulfonylhydrazone 
• 34052-37-4 2-chloro-5-nitrobenzophenone 
• 183110-88-5 2-bromo-5-nitro-benzophenone 

Downstream Products

• 395099-05-5 3-phenyl-1H-indazol-5-amine 
• 599183-30-9 N-tert-Butoxycarbonyl-5-nitro-3-phenyl-1H-indazole 
• 13097-01-3 3-phenyl-1H-indazole 

Relevant articles and documents

INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS

The present invention is directed to indazole and azaindazole compounds which are inhibitors of LRRK2 and are useful in the treatment of CNS disorders.

Indazole compounds, compositions thereof and methods of treatment therewith

This invention is generally directed to the use of Indazole Compounds for treating or preventing diseases associated with protein kinases, including tyrosine kinases, such as proliferative diseases, inflammatory diseases, abnormal angiogenesis and diseases related thereto, atherosclerosis, macular degeneration, diabetes, obesity, pain and others. The methods comprise the administration to a patient in need thereof of an effective amount of an indazole compound that inhibits, modulates or regulates tyrosine kinase signal transduction. Novel indazole compounds or pharmaceutically acceptable salt thereof are presented herein.

Indazole derivatives as JNK inhibitors and compositions and methods related thereto

Compounds having activity as selective inhibitors of JNK are disclosed. The compounds of this invention are indazole derivatives having the following structure: wherein R1, R2 and A are as defined herein. Such compounds have utility in the treatment of a wide range of conditions that are responsive to JNK inhibition. Thus, methods of treating such conditions are also disclosed, as are pharmaceutical compositions containing one or more compounds of the above compounds.